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A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family

Peter Besmer
John E. Murphy
William D. Hardy
Research03 Apr 1986
Nature

Volume: 320, P: 415-421
A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein

Volunteers who develop protection against malaria produce potent antibodies binding to a site of vulnerability on the parasite circumsporozoite protein that is absent in vaccines currently being tested in humans

Joshua Tan
Brandon K Sack
Antonio Lanzavecchia
Research19 Mar 2018
Nature Medicine

Volume: 24, P: 401-407
Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection

Here, the authors use cryo-EM to solve the structures of seven potent human antibodies, and demonstrate in vivo protection in a liver burden assay, using chimeric Plasmodium berghei sporozoites expressing Plasmodium falciparum circumsporozoite protein.

Gregory M. Martin
Jonathan L. Torres
Andrew B. Ward
ResearchOpen Access28 Jul 2023
Nature Communications

Volume: 14, P: 1-16
Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

The most advanced P. falciparum circumsporozoite protein (PfCSP)-based malaria vaccine confers partial protection. Here, Pholcharee et al. present crystal structures, binding affinities/kinetics, and in vivo protection of 8 anti-NANP antibodies to understand in vivo protection of PfCSP-targeting antibodies.

Tossapol Pholcharee
David Oyen
Ian A. Wilson
ResearchOpen Access16 Feb 2021
Nature Communications

Volume: 12, P: 1-14
Multi-level analysis of reproduction in an Antarctic midge identifies female and male accessory gland products that are altered by larval stress and impact progeny viability

Geoffrey Finch
Sonya Nandyal
Joshua B. Benoit
ResearchOpen Access13 Nov 2020
Scientific Reports

Volume: 10, P: 1-27
Low heat tolerance and high desiccation resistance in nocturnal bees and the implications for nocturnal pollination under climate change

Victor H. Gonzalez
Rachel Manweiler
William T. Wcislo
ResearchOpen Access15 Dec 2023
Scientific Reports

Volume: 13, P: 1-12

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A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein

Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

Multi-level analysis of reproduction in an Antarctic midge identifies female and male accessory gland products that are altered by larval stress and impact progeny viability

Low heat tolerance and high desiccation resistance in nocturnal bees and the implications for nocturnal pollination under climate change

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A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein

Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

Multi-level analysis of reproduction in an Antarctic midge identifies female and male accessory gland products that are altered by larval stress and impact progeny viability

Low heat tolerance and high desiccation resistance in nocturnal bees and the implications for nocturnal pollination under climate change

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Quick links