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Showing 1–4 of 4 results
Advanced filters: Author: David P. Klebl Clear advanced filters
  • A study using time-resolved cryogenic electron microscopy reveals the swinging lever mechanism of myosin, providing information on the molecular basis behind the production of force and movement by myosin.

    • David P. Klebl
    • Sean N. McMillan
    • Howard D. White
    ResearchOpen Access
    Nature
    Volume: 642, P: 519-526
  • During clathrin-mediated endocytosis in yeast, endocytic coat adaptors, Sla2 and Ent1, must remain attached to the plasma membrane to transmit force from the actin cytoskeleton required for membrane invagination. Here authors present a cryo-EM structure of a 16-mer complex of the ANTH and ENTH membrane-binding domains from Sla2 and Ent1 bound to PIP2 that constitutes the anchor to the plasma membrane.

    • Javier Lizarrondo
    • David P. Klebl
    • Maria M. Garcia-Alai
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15
  • Serial Lift-Out creates a series of lamellae from one lift-out volume for cryo-ET, increasing the ease and throughput of cryo-lift-out and enabling the study of molecular anatomy in multicellular systems including C. elegans larvae.

    • Oda Helene Schiøtz
    • Christoph J. O. Kaiser
    • Jürgen M. Plitzko
    ResearchOpen Access
    Nature Methods
    Volume: 21, P: 1684-1692