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Advanced filters: Author: David S. A. Haneen Clear advanced filters

CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy

Fry et al. report the first results from a human trial of a CD22-directed chimeric antigen receptor (CAR) T cell therapy providing evidence of efficacy in the treatment of pre–B cell acute lymphoblastic leukemia that is immunotherapy-naive or resistant to CD19-directed CAR T cells.

Terry J Fry
Nirali N Shah
Crystal L Mackall
Research20 Nov 2017
Nature Medicine

Volume: 24, P: 20-28
Synthesis, comprehensive in silico studies, and cytotoxicity evaluation of novel quinazolinone derivatives as potential anticancer agents

David S. A. Haneen
Abdelaal A. Abdalha
Sandy S. Samir
ResearchOpen Access03 Jul 2025
Scientific Reports

Volume: 15, P: 1-25
Identifying organ dysfunction trajectory-based subphenotypes in critically ill patients with COVID-19

Chang Su
Zhenxing Xu
Edward J. Schenck
ResearchOpen Access05 Aug 2021
Scientific Reports

Volume: 11, P: 1-13

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