Nature Search

Charles David Allis (1951–2023)

Ping Chi
Peter W. Lewis
Gang Greg Wang
Comments & Opinion27 Feb 2023
Nature Genetics

Volume: 55, P: 522-523
A pupillometric study of developmental and individual differences in cognitive effort in visual word recognition

Adi Shechter
Ronen Hershman
David L. Share
ResearchOpen Access24 Jun 2022
Scientific Reports

Volume: 12, P: 1-7
Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes

Cells can regulate their mass density. Here, the authors demonstrate how eukaryotes establish and maintain a lower density in the nucleus than in the cytoplasm via pressure balance, and how deviations emerge during pathophysiological states like senescence.

Abin Biswas
Omar Muñoz
Simone Reber
ResearchOpen Access15 Aug 2025
Nature Communications

Volume: 16, P: 1-18
Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release

The histone chaperone nucleoplasmin (Npm) stores histones H2A/H2B in the egg and embryo. Here, the authors use NMR to show that Npm’s intrinsically disordered tail domain controls histone binding at an acidic stretch, which is autoregulated through direct competition with its basic C-terminus.

Christopher Warren
Tsutomu Matsui
David Shechter
ResearchOpen Access20 Dec 2017
Nature Communications

Volume: 8, P: 1-16
A lasting marriage: histones and DNA tie a knot that is here to stay

David Shechter
C. David Allis
Comments & Opinion15 Oct 2007
Nature Reviews Genetics

Volume: 8, P: S23
Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

Sharon Shechter
David R. Thomas
David A. Jans
ResearchOpen Access18 Dec 2017
Scientific Reports

Volume: 7, P: 1-16
WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

An early cellular response to the occurrence of DNA double-strand breaks in mammals is the phosphorylation of the specialized histone variant H2A.X at Ser 139. The chromatin remodelling factor WSTF is found to phosphorylate H2A.X at another site, Tyr 142. Tyrosine phosphorylation has not been observed previously on histones.

Andrew Xiao
Haitao Li
C. David Allis
Research17 Dec 2008
Nature

Volume: 457, P: 57-62
Author Correction: Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

Sharon Shechter
David R. Thomas
David A. Jans
Amendments and CorrectionsOpen Access04 Sept 2018
Scientific Reports

Volume: 8, P: 1
RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription

The formation of blood and lymph vessels after injury requires precise temporal coordination. Here, the authors show that the small GTPase RhoB induces angiogenesis but inhibits lymphangiogenesis in response to dermal wounding by activating different sets of genes in blood vessels and lymphatic endothelial cells.

Damien Gerald
Irit Adini
Laura E. Benjamin
ResearchOpen Access27 Nov 2013
Nature Communications

Volume: 4, P: 1-15
Non-transcriptional control of DNA replication by c-Myc

A new, transcription-independent function for c-Myc is identified. It is found that c-Myc can bind factors involved in DNA replication, thereby causing DNA damage and affecting cell proliferation. This process may also contribute to oncogenesis.

David Dominguez-Sola
Carol Y. Ying
Riccardo Dalla-Favera
Research27 Jun 2007
Nature

Volume: 448, P: 445-451
Single-molecule imaging of transcription dynamics in somatic stem cells

Single-molecule fluorescence in situ hybridization and live-cell imaging are used to study the contribution of transcriptional noise to stem cell heterogeneity, revealing that stochastic transcription dynamics are conducive to concomitant stem-cell maintenance and tissue homeostasis.

Justin C. Wheat
Yehonatan Sella
Ulrich Steidl
Research24 Jun 2020
Nature

Volume: 583, P: 431-436
Novel RU486 (mifepristone) analogues with increased activity against Venezuelan Equine Encephalitis Virus but reduced progesterone receptor antagonistic activity

Aaron DeBono
David R. Thomas
David A. Jans
ResearchOpen Access22 Feb 2019
Scientific Reports

Volume: 9, P: 1-19
ATR and ATM regulate the timing of DNA replication origin firing

David Shechter
Vincenzo Costanzo
Jean Gautier
Research27 Jun 2004
Nature Cell Biology

Volume: 6, P: 648-655
Extraction, purification and analysis of histones

David Shechter
Holger L Dormann
Sandra B Hake
Protocols07 Jun 2007
Nature Protocols

Volume: 2, P: 1445-1457
A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression

H Chen
B Lorton
D Shechter
Research06 Jun 2016
Oncogene

Volume: 36, P: 373-386
DNA replication and progression through S phase

David Y Takeda
Anindya Dutta
Reviews18 Apr 2005
Oncogene

Volume: 24, P: 2827-2843
High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation

Tran et al. combine high throughput sequencing, structural biology and computational simulation to determine the HLA allele and antibody-defined epitope frequencies in renal transplant patients and donors. These results demonstrate the feasibility of HLA epitope matching using data from a national transplantation program.

Jenny N. Tran
Oliver P. Günther
Zoltán Kaló
ResearchOpen Access14 May 2021
Communications Biology

Volume: 4, P: 1-14

Search

Charles David Allis (1951–2023)

A pupillometric study of developmental and individual differences in cognitive effort in visual word recognition

Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes

Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release

A lasting marriage: histones and DNA tie a knot that is here to stay

Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

Author Correction: Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design

RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription

Non-transcriptional control of DNA replication by c-Myc

Single-molecule imaging of transcription dynamics in somatic stem cells

Novel RU486 (mifepristone) analogues with increased activity against Venezuelan Equine Encephalitis Virus but reduced progesterone receptor antagonistic activity

ATR and ATM regulate the timing of DNA replication origin firing

Extraction, purification and analysis of histones

A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression

DNA replication and progression through S phase

High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation

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