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Showing 1–8 of 8 results
Advanced filters: Author: David W. Gotthold Clear advanced filters

  • Carbon-based rods can adsorb water at low humidity and release it at high humidity through a reversible physical process that is associated with the dynamic spacing between rods.

    • Satish K. Nune
    • David B. Lao
    • Herbert T. Schaef
    Research
    Nature Nanotechnology
    Volume: 11, P: 791-797

  • While rheology studies have contributed to the understanding of the viscoelastic properties of living cells, the use of higher frequencies promises elucidate the link between cellular and molecular properties. Here authors introduce a rheological assay that measures the cell mechanical response across a continuous frequency range ≈ 1 – 40 kHz.

    • Gotthold Fläschner
    • Cosmin I. Roman
    • Daniel J. Müller
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10

  • Here the authors characterize structural variations (SVs) in a cohort of individuals with complex genomic rearrangements, identifying breakpoints by employing short- and long-read genome sequencing and investigate their impact on gene expression and the three-dimensional chromatin architecture. They find breakpoints are enriched in inactive regions and can result in chromatin domain fusions.

    • Robert Schöpflin
    • Uirá Souto Melo
    • Stefan Mundlos
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • A picobalance consisting of an optically excited microcantilever has been developed and used to measure the masses of individual healthy and virus-infected cells at high temporal and mass resolutions in culture conditions.

    • David Martínez-Martín
    • Gotthold Fläschner
    • Daniel J. Müller
    Research
    Nature
    Volume: 550, P: 500-505

  • Mechanobiology describes how biological systems respond to mechanical stimuli. This Review surveys basic principles, advantages and limitations of applying and combining atomic force microscopy-based modalities with complementary techniques to characterize the morphology, mechanical properties and functional response of complex biological systems to mechanical cues.

    • Michael Krieg
    • Gotthold Fläschner
    • Daniel J. Müller
    Reviews
    Nature Reviews Physics
    Volume: 1, P: 41-57