Despite great efforts that have focused on anticancer adjuvants, drug resistance in cancer therapy is still a challenging problem. Conventional spherical nanoprobes are unable to effectively destroy the cellular structure in therapy which means the gastric tumor has a high risk of drug resistance. Herein we developed a novel flower-like targeting Fe3O4@Au-HPG-Glc nanoprobe that can rotate along the central axis of the core and substantially destroy the tumor cells by damaging the tumor cells under an alternating magnetic field. The successful application of novel shape-dependent therapy strategy would potentially reduce drug resistance problems of gastric tumors.
- Ting Yin
- Haigang Wu
- Daxiang Cui
