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Advanced filters: Author: Debadrita Bhattacharya Clear advanced filters

Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect

Nishiga and colleagues show therapeutic efficacy for a combination of radiotherapy and CD47 blockade, which also elicits an abscopal effect mediated by macrophages migrating into non-irradiated tumor sites and phagocytosing cancer cells.

Yoko Nishiga
Alexandros P. Drainas
Julien Sage
ResearchOpen Access21 Nov 2022
Nature Cancer

Volume: 3, P: 1351-1366
Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis

Qu et al. identify and characterize reciprocal crosstalk between small-cell lung cancer cells and astrocytes, which mimics neuron–astrocyte interactions during brain development and promotes brain metastasis.

Fangfei Qu
Siqi C. Brough
Julien Sage
Research02 Oct 2023
Nature Cell Biology

Volume: 25, P: 1506-1519

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Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect

Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis

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