Elevated concentrations of the lipid 12,13-diHOME in neonatal faeces is associated with childhood atopy and asthma. Here, the authors identify bacterial epoxide hydrolase genes that produce this lipid, are more abundant in the gut microbiota of neonates who develop atopy and/or asthma and are associated with diminished immune tolerance.
- Sophia R. Levan
- Kelsey A. Stamnes
- Susan V. Lynch
