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Advanced filters: Author: Dessy Chan Clear advanced filters

  • Resistance to 5-fluorouracil and cisplatin (5FU + CDDP) presents a major issue in patients with gastric cancer. Here, the authors establish 5FU + CDDP resistant intestinal gastric cancer patient-derived organoids and identify JAK/STAT-ADAR1 altered lipid metabolism as a regulator of chemoresistance.

    • Tin-Lok Wong
    • Jia-Jian Loh
    • Stephanie Ma
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18