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Nature Biomedical Engineering (1)

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Genetically encoding multiple functionalities into extracellular vesicles for the targeted delivery of biologics to T cells

Biologics can be specifically delivered to T cells by genetically engineering cells to secrete extracellular vesicles that actively load protein cargo and that display high-affinity T-cell-targeting domains and fusogenic glycoproteins.

Devin M. Stranford
Lacy M. Simons
Joshua N. Leonard
Research27 Nov 2023
Nature Biomedical Engineering

Volume: 8, P: 397-414

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Genetically encoding multiple functionalities into extracellular vesicles for the targeted delivery of biologics to T cells

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