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Nature Microbiology (1)

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Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii

Antibiotics to treat carbapenem-resistant Acinetobacter baumannii infection are an urgent need. The cerastecins are potent, bactericidal and efficacious in animal models of infection, and may enable new treatment modalities targeting LOS transport.

Hao Wang
Andrii Ishchenko
Scott S. Walker
Research22 Apr 2024
Nature Microbiology

Volume: 9, P: 1244-1255

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Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii

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