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Advanced filters: Author: Dianren Xia Clear advanced filters

  • This report uncovers a direct link between cancer-driving inflammation and DNA methylation by showing that PGE2 regulates the expression of DNA methylases, resulting in silencing of tumor-suppressor genes. The authors suggest that DNA methylation is an important component of the pathogenic effect of inflammatory signaling in colorectal cancer.

    • Dianren Xia
    • Dingzhi Wang
    • Raymond N DuBois
    Research
    Nature Medicine
    Volume: 18, P: 224-226