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Advanced filters: Author: Dibyanti Mukherjee Clear advanced filters

Structural and molecular basis of choline uptake into the brain by FLVCR2

FLVCR2 is expressed in the blood–brain barrier of mouse and human, and is the major mediator of choline uptake into the brain.

Rosemary J. Cater
Dibyanti Mukherjee
Filippo Mancia
Research01 May 2024
Nature

Volume: 629, P: 704-709
Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity

Microglial states are dynamically regulated during development and disease. Here, the authors show that these changes are mediated by cell autonomous TGF-β signaling in microglia, which is developmentally regulated by ITGB8 in radial glia.

Gabriel L. McKinsey
Nicolas Santander
Thomas D. Arnold
ResearchOpen Access22 Mar 2025
Nature Communications

Volume: 16, P: 1-21

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Structural and molecular basis of choline uptake into the brain by FLVCR2

Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity

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