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Showing 1–7 of 7 results
Advanced filters: Author: Dierk F. Reiff Clear advanced filters
  • Understanding of the fly visual circuitry has been hampered by the difficulty of recording from the small neurons involved. Reiff and colleagues present a technique to record visually evoked responses and find that the L2 interneurons in the medulla encode brightness decrements rather than motion.

    • Dierk F Reiff
    • Johannes Plett
    • Alexander Borst
    Research
    Nature Neuroscience
    Volume: 13, P: 973-978
  • Ramón y Cajal, the founding father of neuroscience, observed similarities between the vertebrate retina and the insect eye, but that was based purely on anatomy. Using state-of-the-art genetics and electrophysiology in the fruitfly, these authors distinguish motion-sensitive neurons responding to abrupt increases in light from those specific to light decrements, thus bringing the similarity with vertebrate circuitry to the functional level.

    • Maximilian Joesch
    • Bettina Schnell
    • Alexander Borst
    Research
    Nature
    Volume: 468, P: 300-304
  • To study long-term changes in neuronal circuits at single-cell resolution, a Troponin C–based Ca2+ indicator protein has been reengineered to increase the signal strength. This allows repeated measurements, over days and weeks, of orientation selective neurons in mouse visual cortex. Hasan et al., also in this issue, describe the use of a similar sensor for recording neuronal activity in vivo.

    • Marco Mank
    • Alexandre Ferrão Santos
    • Oliver Griesbeck
    Research
    Nature Methods
    Volume: 5, P: 805-811
  • This study uses calcium imaging to show that T4 and T5 neurons are divided in specific subpopulations responding to motion in four cardinal directions, and are specific to ON versus OFF edges, respectively; when either T4 or T5 neurons were genetically blocked, tethered flies walking on air-suspended beads failed to respond to the corresponding visual stimuli.

    • Matthew S. Maisak
    • Juergen Haag
    • Alexander Borst
    Research
    Nature
    Volume: 500, P: 212-216