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Integrating single cell expression quantitative trait loci summary statistics to understand complex trait risk genes

The authors describe a new transcriptome-wide association study (TWAS) method that integrates single cell eQTL summary statistics with GWAS data to identify cell type-specific risk genes, together with a cell type-aware drug repurposing pipeline.

Lida Wang
Chachrit Khunsriraksakul
Bibo Jiang
ResearchOpen Access20 May 2024
Nature Communications

Volume: 15, P: 1-13

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