Raza et al. report a naturally occurring animal model that recapitulates cardinal features of Systemic Capillary Leak Syndrome and map its histamine-triggered vascular leak trait to Chromosome 6. They suggest that the predisposition to develop vascular hyperpermeability has a strong genetic component conserved between humans and mice.
- Abbas Raza
- Zhihui Xie
- Kirk M. Druey
