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Showing 1–7 of 7 results
Advanced filters: Author: Dirk-Peter Herten Clear advanced filters

  • Studying lipid nano-domains within the mammalian cell plasma membrane remains a very challenging task. Here, the authors use the solvatochromic probe di-4-ANEPPDHQ, which is sensitive to its biophysical environment, to map membrane nano-environments via single-molecule localisation microscopy.

    • Luca Panconi
    • Jonas Euchner
    • Daniel J. Nieves
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • Methods for imaging the 3D cell surface often require physical interaction. Here the authors report the combination of scanning ion conductance microscopy (SICM) and live-cell super-resolution optical fluctuation imaging (SOFI) for the non-invasive topographical imaging of soft biological samples.

    • Vytautas Navikas
    • Samuel M. Leitao
    • Georg E. Fantner
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9

  • The agrochemical mandipropamid (Mandi), which induces dimerization of a variant of the abscisic acid receptor, has been developed as a new chemical inducer of proximity for cellular and organismal applications.

    • Michael J. Ziegler
    • Klaus Yserentant
    • Richard Wombacher
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 18, P: 64-69

  • Many intracellular pathogens mimic extracellular matrix motifs to specifically interact with the host membrane which may influences virus particle uptake. Here authors use single molecule tension sensors to reveal the minimal forces exerted on single virus particles and demonstrate that the uptake forces scale with the adhesion energy.

    • Tina Wiegand
    • Marta Fratini
    • Joachim P. Spatz
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • It is currently debated how to reliably distinguish liquid–liquid phase separation (LLPS) from other mechanisms. Here the authors report model-free calibrated half-FRAP (MOCHA-FRAP) to probe the barrier at the condensate interface that is responsible for preferential internal mixing in LLPS.

    • Fernando Muzzopappa
    • Johan Hummert
    • Fabian Erdel
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • Fluorescence correlation spectroscopy on crosslinked nanobodies tested on C-type lectin-like receptor 2 (CLEC-2) show different outcomes for divalent and tetravalent nanobody ligands on CLEC-2 clustering, also dependent on CLEC-2 expression levels.

    • Joanne C. Clark
    • Eleyna M. Martin
    • Steve P. Watson
    ResearchOpen Access
    Communications Biology
    Volume: 6, P: 1-17