Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Dmitry Ter-Ovanesyan Clear advanced filters

  • The length of a single guide RNA (gRNA) determines the function of Cas9. In this study 20-nt gRNAs allowed nuclease activity and genome editing, whereas 14-nt gRNAs mediated transcriptional activation or repression.

    • Samira Kiani
    • Alejandro Chavez
    • George Church
    Research
    Nature Methods
    Volume: 12, P: 1051-1054

  • A comparison of seven dCas9-based transcriptional activators shows that VPR, SAM, and Suntag perform best in cell lines from a variety of organisms.

    • Alejandro Chavez
    • Marcelle Tuttle
    • George Church
    Research
    Nature Methods
    Volume: 13, P: 563-567

  • The fusion of three transcriptional activation domains to a nuclease-deficient Cas9 achieves robust induction of gene expression and can induce differentiation of hiPSCs.

    • Alejandro Chavez
    • Jonathan Scheiman
    • George M Church
    Research
    Nature Methods
    Volume: 12, P: 326-328