Extracellular zinc release in glaucoma may affect the key retinal neurotrophic factor PEDF, which binds zinc at intermolecular sites and forms dimers and trimers, losing the ability to recognize PEDF-R and exhibit neurotrophic and antiangiogenic activity.
- Dmitry V. Chistyakov
- Anatolii S. Belousov
- Evgeni Yu. Zernii
