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Advanced filters: Author: Do Hyeon Gim Clear advanced filters

Deciphering cell-type-and temporally specific matrisome expression signatures in human cortical development and neurodevelopmental disorders via scRNA-seq meta-analysis

Human cortical development involves dynamic changes in matrisome gene expression across cell types and developmental stages. Here, authors show that these changes reveal links to neurodevelopmental disorders and provide insights into brain formation and diseases.

Do Hyeon Gim
Muhammad Z. K. Assir
Eunchai Kang
ResearchOpen Access11 Nov 2025
Nature Communications

Volume: 16, P: 1-19
PBK/TOPK mediates Ikaros, Aiolos and CTCF displacement from mitotic chromosomes and alters chromatin accessibility at selected C2H2-zinc finger protein binding sites

PBK is a mitotic kinase implicated in cancer. This study reveals how PBK evicts key C2H2-zinc finger transcription factors such as Ikaros, Aiolos and CTCF from DNA as cells divide, regulating mitotic chromatin accessibility and chromosome compaction.

Andrew Dimond
Do Hyeon Gim
Amanda G. Fisher
ResearchOpen Access23 Sept 2025
Nature Communications

Volume: 16, P: 1-20
Mammalian ubiquitous promoter isolated from proximal regulatory region of bovine MSTN gene

Kyeong-hyeon Eom
Dong-hyeok Kwon
Goo Jang
ResearchOpen Access12 Nov 2024
Scientific Reports

Volume: 14, P: 1-9

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