This study was performed to evaluate role of RORα in mouse testicular structure. Lack of RORα expression induces apoptosis, reduces germ cells differentiation, and may cause infertility. RORα is one of the essential proteins regulating testicular structure. RORα-deficient mice may be a suitable model for studying mutation-induced of human infertility.
- Ramy K. A. Sayed
- Doaa M. Mokhtar
- Darío Acuña-Castroviejo
