Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–7 of 7 results
Advanced filters: Author: Domenick Zero Clear advanced filters

  • Elevated ceramides have been implicated in endothelial dysfunction, preceding cardiometabolic diseases. Yet, direct in vivo evidence is lacking. Here we show that suppression of ceramides and S1P are causally linked to endothelial dysfunction contributing to cardiometabolic disease in obese mice

    • Luisa Rubinelli
    • Onorina Laura Manzo
    • Annarita Di Lorenzo
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • Ferumoxytol (Fer) is an FDA-approved iron oxide formulation that disrupts caries-causing biofilms with high specificity but cannot interfere with enamel acid demineralization. Here, Fer is combined with stannous fluoride (SnF2), resulting in enhanced stability of SnF2 and inhibition of both biofilm accumulation and enamel damage more effectively than either alone.

    • Yue Huang
    • Yuan Liu
    • Hyun Koo
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • Savage and colleagues identify a population of CD4+ T cells within the endogenous repertoire that exhibit hallmarks of overt self-reactivity, spontaneously adopt a follicular helper T cell phenotype and are enriched in non-lymphoid organs following sustained Treg cell depletion.

    • Victoria Lee
    • Donald M. Rodriguez
    • Peter A. Savage
    Research
    Nature Immunology
    Volume: 24, P: 487-500

  • Ferumoxytol is a nanoparticle formulation approved for systemic use to treat iron deficiency. Liu et al. show that topical use of ferumoxytol, in combination with low concentrations of H2O2, disrupts intractable oral biofilms and prevents tooth decay in vitro and in an animal model.

    • Yuan Liu
    • Pratap C. Naha
    • Hyun Koo
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12

  • It remains difficult to distinguish cognate APC–T cell interactions in human tissue sections. Clark and colleagues have developed an imaging–machine-learning pipeline that uses deep convolutional and tuned neural networks to identify the combination of distance and cell-shape features that can discriminate between bystander human APC–T cell interactions and cognate interactions in situ.

    • Vladimir M. Liarski
    • Adam Sibley
    • Marcus R. Clark
    Research
    Nature Immunology
    Volume: 20, P: 503-513

  • The formation of dental caries involves the interaction between the tooth, the microbial biofilm at the tooth surface and dietary sugars. This Primer by Pitts et al. aims to provide a global overview of caries, focusing on current, patient-centred, tooth-preserving preventive care.

    • Nigel B. Pitts
    • Domenick T. Zero
    • Amid Ismail
    Reviews
    Nature Reviews Disease Primers
    Volume: 3, P: 1-16