Nature Search

Inferring seal populations from lake sediments

Dominic A. Hodgson
Nadine M. Johnston
Research01 May 1997
Nature

Volume: 387, P: 30-31
Holocene dynamics of the Southern Hemisphere westerly winds and possible links to CO₂ outgassing

The strength of the Southern Hemisphere westerly winds varied throughout the Holocene, according to a reconstruction from lake sediments, with periods of stronger winds coincident with higher atmospheric CO₂ levels.

Krystyna M. Saunders
Stephen J. Roberts
Dominic A. Hodgson
Research23 Jul 2018
Nature Geoscience

Volume: 11, P: 650-655
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

Dominic Kwiatkowski and colleagues report analysis of genetic variation in 826 Plasmodium falciparum samples collected from 10 locations in West Africa and southeast Asia. They characterize the population structure of this parasite in Cambodia and find evidence for multiple distinct subpopulations showing high levels of genetic differentiation and artemisinin resistance.

Olivo Miotto
Jacob Almagro-Garcia
Dominic P Kwiatkowski
Research28 Apr 2013
Nature Genetics

Volume: 45, P: 648-655
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Sustained greening of the Antarctic Peninsula observed from satellites

Analyses of satellite observations from 1986 to 2021 suggest that the Antarctic Peninsula is greening at an accelerated rate.

Thomas P. Roland
Oliver T. Bartlett
Andrew Fleming
ResearchOpen Access04 Oct 2024
Nature Geoscience

Volume: 17, P: 1121-1126
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
A novel locus of resistance to severe malaria in a region of ancient balancing selection

A multi-centre genome-wide association study of severe malaria in African children uncovers a new resistance locus close to a cluster of genes encoding glycophorins, which are receptors used by the malaria-causing parasite to invade red blood cells.

Gavin Band
Kirk A. Rockett
Victoria Cornelius
Research30 Sept 2015
Nature

Volume: 526, P: 253-257
Self-control during response conflict by human supplementary eye field

Masud Husain
Andrew Parton
Geraint Rees
Research21 Jan 2003
Nature Neuroscience

Volume: 6, P: 117-118
Southern westerlies and CO₂

The Southern Hemisphere westerly winds affect the exchange of carbon dioxide between the ocean and atmosphere. Climate reconstructions from the southern mid-latitudes may reveal variability in the strength and position of the wind belt since the Last Glacial Maximum.

Dominic A. Hodgson
Louise C. Sime
News & Views30 Sept 2010
Nature Geoscience

Volume: 3, P: 666-667
SARS-CoV-2 evolution during treatment of chronic infection

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Research05 Feb 2021
Nature

Volume: 592, P: 277-282
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Research11 Mar 2021
Nature

Volume: 593, P: 136-141
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Major advance of South Georgia glaciers during the Antarctic Cold Reversal following extensive sub-Antarctic glaciation

The glaciated history of South Georgia is debated, with many suggesting a coastal limit to the island’s ice cap during the last glaciation. Here, the authors show extensive ice-cap cover of the continental block during this time and a readvance of glaciers to fjord mouths during the Antarctic Cold Reversal.

Alastair G. C. Graham
Gerhard Kuhn
Gerhard Bohrmann
ResearchOpen Access17 Mar 2017
Nature Communications

Volume: 8, P: 1-15
Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm

Two complementary coiled-coil peptides and a bacterial microcompartment shell protein are combined to construct cytoscaffolds within Escherichia coli cells. Targeting enzymes to the cytoplasmic scaffold results in colocalization and improved metabolic flux.

Matthew J Lee
Judith Mantell
Martin J Warren
Research11 Dec 2017
Nature Chemical Biology

Volume: 14, P: 142-147
Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination

Intravital imaging reveals macrophage-driven de novo induction of cancer stem cells in vivo, and their dramatic enrichment on dissemination through TMEM doorways. These findings provide a mechanism for the validated ability of TMEM doorway density to be prognostic for distant recurrence of metastatic tumors in breast cancer patients.

Ved P. Sharma
Binwu Tang
Maja H. Oktay
ResearchOpen Access15 Dec 2021
Nature Communications

Volume: 12, P: 1-24
Past penguin colony responses to explosive volcanism on the Antarctic Peninsula

Changes in penguin populations on the Antarctic Peninsula in recent decades have been linked to environmental factors such as sea ice. Here, the authors show that penguin colony change on Ardley Island, NW Antarctic Peninsula during the last 8,500 years was primarily driven by volcanic activity.

Stephen J. Roberts
Patrick Monien
Dominic A. Hodgson
ResearchOpen Access11 Apr 2017
Nature Communications

Volume: 8, P: 1-16
Adeno-associated virus 2 infection in children with non-A–E hepatitis

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Antonia Ho
Richard Orton
Emma C. Thomson
Research30 Mar 2023
Nature

Volume: 617, P: 555-563
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Measurements of subclonal expansion of ctDNA in the plasma before surgery may enable the prediction of future metastatic subclones, offering the possibility for early intervention in patients with non-small-cell lung cancer.

Christopher Abbosh
Alexander M. Frankell
Charles Swanton
Research13 Apr 2023
Nature

Volume: 616, P: 553-562
Author Correction: Past penguin colony responses to explosive volcanism on the Antarctic Peninsula

Stephen J. Roberts
Patrick Monien
Dominic A. Hodgson
Amendments and CorrectionsOpen Access07 Jun 2022
Nature Communications

Volume: 13, P: 1
Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania

Four genome-wide associated loci are currently known for malaria susceptibility. Here, the authors expand on earlier work by combining data from 11 malaria-endemic countries and additional population sequencing informing an African-enriched imputation reference panel, with findings including a previously unreported association on chromosome 6.

Gavin Band
Quang Si Le
Dominic P. Kwiatkowski
ResearchOpen Access16 Dec 2019
Nature Communications

Volume: 10, P: 1-19
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Chris Varghese
Luke Peters
Caroline Reinke
ResearchOpen Access26 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-16
Poleward displacement of the Southern Hemisphere Westerlies in response to Early Holocene warming

Southern Hemisphere Westerlies were poleward of their current position during the Early Holocene, as suggested by diatom-inferred sea salt aerosol and lake sediment geochemistry from Cape Horn.

Bianca B. Perren
Jérôme Kaiser
Frank Lamy
ResearchOpen Access28 Feb 2025
Communications Earth & Environment

Volume: 6, P: 1-10
Parkinson’s families project: a UK-wide study of early onset and familial Parkinson’s disease

Clodagh Towns
Zih-Hua Fang
Raquel Real
ResearchOpen Access17 Oct 2024
npj Parkinson's Disease

Volume: 10, P: 1-13
FLT3 inhibitors as MRD-guided salvage treatment for molecular failure in FLT3 mutated AML

Jad Othman
Nicola Potter
Richard Dillon
ResearchOpen Access09 Aug 2023
Leukemia

Volume: 37, P: 2066-2072
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Southward migration of the Southern Hemisphere westerly winds corresponds with warming climate over centennial timescales

Warmer periods correspond with poleward migration of the Southern Hemisphere westerly winds over the past 700 years and vice versa, according to multi-proxy records from a lake sediment core on sub-Antarctic Marion Island.

Bianca B. Perren
Dominic A. Hodgson
Wim Vyverman
ResearchOpen Access09 Dec 2020
Communications Earth & Environment

Volume: 1, P: 1-8
A dataset of Antarctic ecosystems in ice-free lands: classification, descriptions, and maps

Anikó B. Tóth
Aleks Terauds
David A. Keith
ResearchOpen Access22 Jan 2025
Scientific Data

Volume: 12, P: 1-16

Search

Inferring seal populations from lake sediments

Holocene dynamics of the Southern Hemisphere westerly winds and possible links to CO₂ outgassing

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Sustained greening of the Antarctic Peninsula observed from satellites

Mapping the human genetic architecture of COVID-19

Genomic investigations of unexplained acute hepatitis in children

A novel locus of resistance to severe malaria in a region of ancient balancing selection

Self-control during response conflict by human supplementary eye field

Southern westerlies and CO₂

SARS-CoV-2 evolution during treatment of chronic infection

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

A second update on mapping the human genetic architecture of COVID-19

Whole-genome sequencing reveals host factors underlying critical COVID-19

Major advance of South Georgia glaciers during the Antarctic Cold Reversal following extensive sub-Antarctic glaciation

Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm

Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination

Past penguin colony responses to explosive volcanism on the Antarctic Peninsula

Adeno-associated virus 2 infection in children with non-A–E hepatitis

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Author Correction: Past penguin colony responses to explosive volcanism on the Antarctic Peninsula

Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Poleward displacement of the Southern Hemisphere Westerlies in response to Early Holocene warming

Parkinson’s families project: a UK-wide study of early onset and familial Parkinson’s disease

FLT3 inhibitors as MRD-guided salvage treatment for molecular failure in FLT3 mutated AML

Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Southward migration of the Southern Hemisphere westerly winds corresponds with warming climate over centennial timescales

A dataset of Antarctic ecosystems in ice-free lands: classification, descriptions, and maps

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