Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Advertisement

Nature

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Nature (20)
Nature Communications (8)
Nature Immunology (7)
Pediatric Research (5)
Nature Genetics (5)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (47)
News & Views (3)
Amendments and Corrections (2)
Reviews (2)
Correspondence (1)

Subject Check one or more subjects to show results from those subjects only.

Biochemistry
Biological techniques
Cardiology
Cell biology
Chemical biology
Computational biology and bioinformatics
Developmental biology
Diseases
Genetics
Immunology
Mathematics and computing
Medical research
Microbiology
Physiology
Stem cells

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–50 of 55 results

Advanced filters: Author: Donald Metcalf Clear advanced filters

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

Nicholas M. Gough
Jill Gough
Ashley R. Dunn
Research28 Jun 1984
Nature

Volume: 309, P: 763-767
Multiple Thymus Grafts in Aged Mice

DONALD METCALF
Research01 Oct 1965
Nature

Volume: 208, P: 87-88
Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells

Nicos A. Nicola
Colin G. Begley
Donald Metcalf
Research18 Apr 1985
Nature

Volume: 314, P: 625-628
Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia

Thomas J. Gonda
Donald Metcalf
Research19 Jul 1984
Nature

Volume: 310, P: 249-251
Delayed Effect of Thymectomy in Adult Life on Immunological Competence

DONALD METCALF
Research01 Dec 1965
Nature

Volume: 208, P: 1336
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

R. Lindsay Williams
Douglas J. Hilton
Nicholas M. Gough
Research15 Dec 1988
Nature

Volume: 336, P: 684-687
Production of Leukemia Inhibitory Factor in Escherichia coli by a Novel Procedure and Its Use in Maintaining Embryonic Stem Cells in Culture

David P. Gearing
Nicos A. Nicola
R. Lindsay Williams
Research01 Nov 1989
Bio/Technology

Volume: 7, P: 1157-1161
Thrombopoietin — at last

Donald Metcalf
News & Views16 Jun 1994
Nature

Volume: 369, P: 519-520
Erythrocyte Osmotic Fragility in AKR Mice with Lymphoid Leukæmia

MARGARET WIADROWSKI
DONALD METCALF
Research15 Jun 1963
Nature

Volume: 198, P: 1103-1104
A Thymus Responsive Phase in Leukæmogenesis in AKR Mice

DONALD METCALF
Research07 Jul 1962
Nature

Volume: 195, P: 88-89
Another way to generate T cells?

Oncostatin M stimulates extrathymic generation of T lymphocytes.

Donald Metcalf
News & Views01 Jan 1997
Nature Medicine

Volume: 3, P: 18-19
cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions

cellSTAAR advances noncoding rare variant association analysis by integrating single-cell genomics data.

Eric Van Buren
Yi Zhang
Xihong Lin
Research31 Dec 2025
Nature Methods

Volume: 23, P: 338-349
BCR – ABL activates pathways mediating cytokine independence and protection against apoptosis in murine hematopoietic cells in a dose-dependent manner

Nathalie Cambier
Rajesh Chopra
Andrew G Elefanty
Research26 Jan 1998
Oncogene

Volume: 16, P: 335-348
A regional acidic cloud/fog water event in the eastern United States

Kathleen C. Weathers
Gene E. Likens
Daniel Smiley
Research20 Feb 1986
Nature

Volume: 319, P: 657-658
Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

Kenneth Kaushansky
Si Lok
Donald C. Foster
Research16 Jun 1994
Nature

Volume: 369, P: 568-571
Expression of the c-fms proto-oncogene during human monocytic differentiation

Eric Sariban
Thomas Mitchell
Donald Kufe
Research04 Jul 1985
Nature

Volume: 316, P: 64-66
Origin of ultra-high-energy γ-rays from Cygnus X-3 and related sources

Demosthenes Kazanas
Donald C. Ellison
Research01 Jan 1986
Nature

Volume: 319, P: 380-382
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

Using data from a single time point, passenger-approximated clonal expansion rate (PACER) estimates the fitness of common driver mutations that lead to clonal haematopoiesis and identifies TCL1A activation as a mediator of clonal expansion.

Joshua S. Weinstock
Jayakrishnan Gopakumar
Siddhartha Jaiswal
Research12 Apr 2023
Nature

Volume: 616, P: 755-763
Modulation of Neonatal Neutrophil Function by Pentoxifylline

Peter J Krause
Eufronio G Maderazo
Donald L Kreutzer
Research01 Feb 1991
Pediatric Research

Volume: 29, P: 123-127
A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies

MultiSTAAR provides a general and flexible statistical framework for functionally informed multi-trait rare variant analysis of biobank-scale sequencing studies by jointly analyzing multiple traits and incorporating annotation information.

Xihao Li
Han Chen
Xihong Lin
Research07 Feb 2025
Nature Computational Science

Volume: 5, P: 125-143
New Type of Colony-forming Cell located in the Pleural Cavity

DONALD METCALF
Correspondence23 Aug 1972
Nature New Biology

Volume: 238, P: 253-254
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Analysis of whole-genome sequences of 25,465 individuals of European ancestry shows that rare variants contribute substantially to the heritability of height and body mass index.

Pierrick Wainschtein
Deepti Jain
Peter M. Visscher
Research07 Mar 2022
Nature Genetics

Volume: 54, P: 263-273
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

The influence of X chromosome genetic variation on blood lipids and coronary heart disease (CHD) is not well understood. Here, the authors analyse X chromosome sequencing data across 65,322 multi-ancestry individuals, identifying associations of the Xq23 locus with lipid changes and reduced risk of CHD and diabetes mellitus.

Pradeep Natarajan
Akhil Pampana
Gina M. Peloso
ResearchOpen Access12 Apr 2021
Nature Communications

Volume: 12, P: 1-14
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Both rare and common variants contribute to the aetiology of complex traits such as type 2 diabetes (T2D). Here, the authors examine the effect of coding variation on glycaemic traits and T2D, and identify low-frequency variation in GLP1Rsignificantly associated with these traits.

Jennifer Wessel
Audrey Y Chu
Mark O Goodarzi
ResearchOpen Access29 Jan 2015
Nature Communications

Volume: 6, P: 1-16
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk

Analyses of genome and exome sequencing data identify rare coding and structural variants associated with atrial fibrillation and highlight genetic links between atrial fibrillation and cardiomyopathies.

Seung Hoan Choi
Sean J. Jurgens
Patrick T. Ellinor
Research06 Mar 2025
Nature Genetics

Volume: 57, P: 548-562
The fascinating life of hematopoietic stem cells

Saul Sharkis
Lothar Kanz
Donald Orlic
News & Views01 Oct 1998
Nature Medicine

Volume: 4, P: 1118-1119
The colony-stimulating factors and cancer

The four colony-stimulating factors (CSFs) regulate the generation and some functions of granulocytes and macrophages, and recombinant granulocyte-CSF and granulocyte–macrophage-CSF are used to treat patients with reduced white blood cell levels. How did we come to our understanding of the CSFs and what might the future opportunities be?

Donald Metcalf
Reviews01 Jun 2010
Nature Reviews Cancer

Volume: 10, P: 425-434
Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

Axel Kallies
Edwin D Hawkins
Stephen L Nutt
Research26 Mar 2006
Nature Immunology

Volume: 7, P: 466-474
Characterization of Nonmotile Neutrophil Subpopulations in Neonates and Adults

Peter J Krause
Donald L Kreutzer
Nadia Greca
Research01 May 1989
Pediatric Research

Volume: 25, P: 519-524
Gigantism in mice lacking suppressor of cytokine signalling-2

Donald Metcalf
Christopher J. Greenhalgh
Warren S. Alexander
Research29 Jun 2000
Nature

Volume: 405, P: 1069-1073
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

Vanessa S. Marsden
Liam O'Connor
Andreas Strasser
Research25 Sept 2002
Nature

Volume: 419, P: 634-637
A family of cytokine-inducible inhibitors of signalling

Robyn Starr
Tracy A. Willson
Douglas J. Hilton
Research26 Jun 1997
Nature

Volume: 387, P: 917-921
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

Necroptosis is a regulated form of inflammatory cell death driven by activated MLKL. Here, the authors identify a mutation in the brace region that confers constitutive activation, leading to lethal inflammation in homozygous mutant mice and providing insight into human mutations in this region.

Joanne M. Hildebrand
Maria Kauppi
John Silke
ResearchOpen Access19 Jun 2020
Nature Communications

Volume: 11, P: 1-16
Whole genome sequence analysis of blood lipid levels in >66,000 individuals

Although the common genetic variants contributing to blood lipid levels have been studied, the contribution of rare variants is less understood. Here, the authors perform a rare coding and noncoding variant association study of blood lipid levels using whole genome sequencing data.

Margaret Sunitha Selvaraj
Xihao Li
Pradeep Natarajan
ResearchOpen Access11 Oct 2022
Nature Communications

Volume: 13, P: 1-18
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

STAARpipeline is a comprehensive framework for flexible and scalable rare-variant association analysis using whole-genome sequencing data and annotation information.

Zilin Li
Xihao Li
Xihong Lin
Research27 Oct 2022
Nature Methods

Volume: 19, P: 1599-1611
Clonal haematopoiesis and risk of chronic liver disease

A study shows that clonal haematopoiesis of indeterminate potential is associated with an increased risk of chronic liver disease specifically through the promotion of liver inflammation and injury.

Waihay J. Wong
Connor Emdin
Pradeep Natarajan
Research12 Apr 2023
Nature

Volume: 616, P: 747-754
SOCS3 negatively regulates IL-6 signaling in vivo

Ben A Croker
Danielle L Krebs
Warren S Alexander
Research18 May 2003
Nature Immunology

Volume: 4, P: 540-545
Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

Jennifer E Fenner
Robyn Starr
Paul J Hertzog
Research27 Nov 2005
Nature Immunology

Volume: 7, P: 33-39
Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways

Platelet production has been suggested to occur by apoptosis of megakaryocytes, but mitochondrially mediated apoptosis is known to be dispensable. Here, the authors show that death receptor-mediated apoptosis in mouse megakaryocytes is also not required for platelet biogenesis.

Emma C. Josefsson
Deborah L. Burnett
Benjamin T. Kile
Research17 Mar 2014
Nature Communications

Volume: 5, P: 1-14
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Most studies of the genetics of the metabolome have been done in individuals of European descent. Here, the authors integrate genomics and metabolomics in Black individuals, highlighting the value of whole genome sequencing in diverse populations and linking circulating metabolites to human disease.

Usman A. Tahir
Daniel H. Katz
Robert E. Gerszten
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-16
Genome sequencing unveils a regulatory landscape of platelet reactivity

Platelet aggregation is associated with myocardial infarction and stroke. Here, the authors have conducted a whole genome sequencing association study on platelet aggregation, discovering a locus in RGS18, where enhancer assays suggest an effect on activity of haematopoeitic lineage transcription factors.

Ali R. Keramati
Ming-Huei Chen
Andrew D. Johnson
ResearchOpen Access15 Jun 2021
Nature Communications

Volume: 12, P: 1-13
Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

Pooling participant-level genetic data into a single analysis can result in variance stratification, reducing statistical performance. Here, the authors develop variant-specific inflation factors to assess variance stratification and apply this to pooled individual-level data from whole genome sequencing.

Tamar Sofer
Xiuwen Zheng
Kenneth M. Rice
ResearchOpen Access09 Jun 2021
Nature Communications

Volume: 12, P: 1-14
Hydrophobic Surfactant-Associated Protein in Whole Lung Surfactant and Its Importance for Biophysical Activity in Lung Surfactant Extracts Used for Replacement Therapy

Jeffrey A Whitesst
Bryan L Ohning
Robert H Notter
Research01 May 1986
Pediatric Research

Volume: 20, P: 460-467
Expression of the Complement Receptors CR1 and CR3 and the Type III Fc_γ Receptor on Neutrophils from Newborn Infants and from Fetuses with Rh Disease

Jeffrey B Smith
Donald E Campbell
Mary Catherine Harris
Research01 Aug 1990
Pediatric Research

Volume: 28, P: 120-126
In Vitro and In Vivo Effects of Granulocyte Colony-Stimulating Factor on Neutrophils in Glycogen Storage Disease Type IB: Granulocyte Colony-Stimulating Factor Therapy Corrects the Neutropenia and the Defects in Respiratory Burst Activity and Ca²⁺ Mobilization

Lisa J Mccawley
Helen M Korchak
Laurie Kilpatrick
Research01 Jan 1994
Pediatric Research

Volume: 35, P: 84-90
Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo

Shalin H Naik
Priyanka Sathe
Ken Shortman
Research07 Oct 2007
Nature Immunology

Volume: 8, P: 1217-1226
Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes

Shalin H Naik
Donald Metcalf
Ken Shortman
Research07 May 2006
Nature Immunology

Volume: 7, P: 663-671
The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells

Ets family transcription factors function in mammalian development. Kile and colleagues demonstrate that the Ets family member Erg is essential for definitive hematopoiesis and adult hematopoietic stem cell function.

Stephen J Loughran
Elizabeth A Kruse
Benjamin T Kile
Research25 May 2008
Nature Immunology

Volume: 9, P: 810-819
Granulocyte colony-stimulating factor and neutrophils—forgotten mediators of inflammatory disease

Neutrophils are powerful mediators of tissue inflammation, and the balance between neutrophil survival and clearance is crucial to the resolution of inflammation. The cytokine granulocyte colony-stimulating factor is an important regulator of neutrophil production and survival. This Review discusses the roles of neutrophils and granulocyte colony-stimulating factor in chronic inflammatory diseases.

Jo L Eyles
Andrew W Roberts
Ian P Wicks
Reviews01 Sept 2006
Nature Clinical Practice Rheumatology

Volume: 2, P: 500-510
Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1

Nicholas D Huntington
Hamsa Puthalakath
Andreas Strasser
Research08 Jul 2007
Nature Immunology

Volume: 8, P: 856-863

Previous page
page 1
page 2
Next page

Search

Search articles by subject, keyword or author

Show results from

Advanced search

Quick links

Explore articles by subject
Find a job
Guide to authors
Editorial policies

Nature.com

nature.com footer links

About Nature Portfolio

About us
Press releases
Press office
Contact us

Discover content

Journals A-Z
Articles by subject
protocols.io
Nature Index

Publishing policies

Nature portfolio policies
Open access

Author & Researcher services

Reprints & permissions
Research data
Language editing
Scientific editing
Nature Masterclasses
Research Solutions

Libraries & institutions

Librarian service & tools
Librarian portal
Open research
Recommend to library

Advertising & partnerships

Advertising
Partnerships & Services
Media kits
Branded content

Professional development

Nature Awards
Nature Careers
Nature Conferences

Regional websites

Nature Africa
Nature China
Nature India
Nature Japan
Nature Middle East

Privacy Policy
Use of cookies
Legal notice
Accessibility statement
Terms & Conditions
Your US state privacy rights

© 2026 Springer Nature Limited