Nature Search

Genomic epidemiology of the 2025 mpox epidemic in Sierra Leone

A phylogenetic analysis examined the origins of the first mpox outbreak in Sierra Leone and found evidence of an emerging lineage (G.1) that has likely descended from the Nigerian epidemic and emerged in Sierra Leone months before first detection.

Allan K. O. Campbell
John Demby Sandi
Donald S. Grant
ResearchOpen Access12 May 2026
Nature Medicine

Volume: 32, P: 1917-1926
Increase in wild animal consumption across Central Africa

Wild meat is a fundamental component of the diets of rural Central African populations, accounting for 20% of the recommended daily protein intake, compared with 13% and 6% for those living in towns and cities.

Mattia Bessone
Daniel J. Ingram
Lauren Coad
ResearchOpen Access29 Apr 2026
Nature

Volume: 653, P: 1092-1098
Genetics and evolution of female choice

M. E. N. Majerus
P. O'Donald
H. Ireland
Research08 May 1986
Nature

Volume: 321, P: 164-167
Genome-wide association and population-tailored polygenic risk for Parkinson’s disease in Taiwan

Yung-Tsai Chu
Yu-An Su
Masharip Atadzhanov
ResearchOpen Access22 May 2026
npj Parkinson's Disease

P: 1-14
Expression of Xist in mouse germ cells correlates with X–chromosome inactivation

John R. McCarrey
Donald D. Dilworth
Research01 Nov 1992
Nature Genetics

Volume: 2, P: 200-203
Observations of Ionization induced by Artificial Earth Satellites

JOHN D. KRAUS
ROBERT C. HIGGY
W. REED CRONE
Research20 Feb 1960
Nature

Volume: 185, P: 520-521
Biomarkers of response to neoadjuvant palbociclib plus anastrozole in endocrine-resistant estrogen receptor-positive/HER2-negative breast cancer: a phase 2 trial

CDK4/6 inhibitors are promising treatments for ER+ breast cancer, however resistance remains a challenge. Here, the authors analyse the NeoPalANA cohort and indicate that a 33 gene signature was predictive of response to neoadjuvant anastrozole and palbociclib.

Tim Kong
Alex Mabry
Cynthia X. Ma
ResearchOpen Access27 Jan 2026
Nature Communications

Volume: 17, P: 1-17
Whole-genome sequences of 240 indigenous African cattle from Egypt, Uganda, and South Africa

Njabulo Dlamini
Junxin Gao
Richard P. M. A. Crooijmans
ResearchOpen Access19 May 2026
Scientific Data

P: 1-13
Herpesvirus-transformed cytotoxic T-cell lines

Donald R. Johnson
Mikael Jondal
Research07 May 1981
Nature

Volume: 291, P: 81-83
A haemoprotein with kinase activity encoded by the oxygen sensor of Rhizobium meliloti

Marie A. Gilles-Gonzalez
Gary S. Ditta
Donald R. Helinski
Research14 Mar 1991
Nature

Volume: 350, P: 170-172
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

Si Lok
Kenneth Kaushansky
Donald C. Foster
Research16 Jun 1994
Nature

Volume: 369, P: 565-568
Genome instability in a region of human DNA enriched in Alu repeat sequences

Bruno Calabretta
Donald L. Robberson
Grady F. Saunders
Research18 Mar 1982
Nature

Volume: 296, P: 219-225
Receptor binding and internalization of immobilized transcobalamin II by mouse leukaemia cells

Kiyoshi Takahashi
Mehdi Tavassoli
Donald W. Jacobsen
Research18 Dec 1980
Nature

Volume: 288, P: 713-715
Effect of Aminopterin on the Replication of the Murine Salivary Gland Virus

DONALD HENSON
HENRY PINKERTON
Research25 Apr 1964
Nature

Volume: 202, P: 419-420
Relationship of Electrical Potential Differences to Net Ion Fluxes in Rat Proximal Tubules

DONALD MARSH
SIDNEY SOLOMON
Research15 Feb 1964
Nature

Volume: 201, P: 714-715
Neolithic resinated wine

Patrick E. McGovern
Donald L. Glusker
Mary M. Voigt
Research06 Jun 1996
Nature

Volume: 381, P: 480-481
New Hypothesis of Insulin Secretion

PAUL E. LACY
SIMON L. HOWELL
C. JOAN FINK
Research14 Sept 1968
Nature

Volume: 219, P: 1177-1179
Large rate accelerations in antibody catalysis by strategic use of haptenic charge

Simon N. Thorn
Richard G. Daniels
Donald Hilvert
Research19 Jan 1995
Nature

Volume: 373, P: 228-230
Photoinduced Free Radicals of Visual Pigments in Solutions mobile at −196° C

ROBERT SACK
DONALD C. BORG
SIMON FREED
Research28 Jan 1972
Nature

Volume: 235, P: 224-226
Neoadjuvant cabozantinib for locally advanced nonmetastatic clear cell renal cell carcinoma: a phase 2 trial

Bilen et al. perform a phase 2 single-arm clinical trial of neoadjuvant cabozantinib in patients with locally advanced nonmetastatic clear cell renal cell carcinoma, assess efficacy and find antitumor CD8⁺ T cell response activation upon treatment.

Mehmet A. Bilen
BaoHan T. Vo
Viraj A. Master
Research27 Feb 2025
Nature Cancer

Volume: 6, P: 432-444
Association of cellular membrane of E. coli minicells with the origins/terminus region of replication of plasmid ColEl DNA

ROBERT B. SPARKS JR
DONALD R. HELINSKI
Research01 Feb 1979
Nature

Volume: 277, P: 572-575
Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Large genome-wide meta-analysis of clinically diagnosed late-onset Alzheimer’s disease (LOAD) from 94,437 individuals identifies new LOAD risk loci and implicates Aβ formation, tau protein binding, immune response and lipid metabolism.

Brian W. Kunkle
Benjamin Grenier-Boley
Margaret A. Pericak-Vance
Research28 Feb 2019
Nature Genetics

Volume: 51, P: 414-430
A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
Do protons block Na⁺ channels by binding to a site outside the pore?

Donald T. Campbell
Research08 Jul 1982
Nature

Volume: 298, P: 165-167
Unidirectional replication of plasmid ColE1 DNA

MICHAEL A. LOVETT
LEONARD KATZ
DONALD R. HELINSKI
Research27 Sept 1974
Nature

Volume: 251, P: 337-340
A saturated map of common genetic variants associated with human height

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

Loïc Yengo
Sailaja Vedantam
Joel N. Hirschhorn
ResearchOpen Access12 Oct 2022
Nature

Volume: 610, P: 704-712
Identification of overoxidizing and non-overoxidizing NAD-dependent methanol dehydrogenases and implications for synthetic methylotrophy

Formate produced by synthetic methylotrophic E. coli can lead to carbon loss and negatively impact bioproduction efficiency. Here, the authors report the production of formate as a widespread property of NAD-dependent methanol dehydrogenases and identify Mdhs without this overoxidation activity.

Philipp Keller
Emese Hegedis
Julia A. Vorholt
ResearchOpen Access09 Dec 2025
Nature Communications

Volume: 16, P: 1-15
I and brain

Donald Michie
Books & Arts19 Nov 1981
Nature

Volume: 294, P: 291-292
Meta-analyses identify DNA methylation associated with kidney function and damage

Many genetic loci have been identified to be associated with kidney disease, but the molecular mechanisms are not well understood. Here, the authors perform epigenome-wide association studies on kidney function measures to identify epigenetic marks and pathways involved in kidney function.

Pascal Schlosser
Adrienne Tin
Alexander Teumer
ResearchOpen Access09 Dec 2021
Nature Communications

Volume: 12, P: 1-16
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus

Serum urate concentration can be studied in large datasets to find genetic and epigenetic loci that may be related to cardiometabolic traits. Here the authors identify and replicate 100 urate-associated CpGs, which provide insights into urate GWAS loci and shared CpGs of urate and cardiometabolic traits.

Adrienne Tin
Pascal Schlosser
Anna Köttgen
ResearchOpen Access09 Dec 2021
Nature Communications

Volume: 12, P: 1-18
Sequence of an unusually large protein implicated in regulation of myosin activity in C. elegans

Guy M. Benian
Jane E. Kiff
Robert H. Waterston
Research02 Nov 1989
Nature

Volume: 342, P: 45-50
Machines and the Theory of Intelligence

DONALD MICHIE
Research23 Feb 1973
Nature

Volume: 241, P: 507-512
A dimerization motif for transmembrane α–helices

Mark A. Lemmon
Herbert R. Treutlein
Donald M. Engelman
Research01 Mar 1994
Nature Structural Biology

Volume: 1, P: 157-163
Varicella-zoster virus DNA in human sensory ganglia

Donald H. Gilden
Abbas Vafai
Mary Wellish
Research01 Dec 1983
Nature

Volume: 306, P: 478-480
Minor-element signature of relic olivine grains in deep-sea particles—a match with forsterites from C2 meteorites

Ian M. Steele
Joseph V. Smith
Donald E. Brownlee
Research24 Jan 1985
Nature

Volume: 313, P: 297-299
Agonist–antagonist properties of N-allyl-[D-Ala]²-Met-enkephalin

CANDACE B. PERT
DONALD L. BOWIE
ERHARD GROSS
Research01 Sept 1977
Nature

Volume: 269, P: 73-75
Transcription in oocytes of highly methylated rDNA from Xenopus laevis sperm

Donald Macleod
Adrian Bird
Research10 Nov 1983
Nature

Volume: 306, P: 200-203
Virus genomes reveal factors that spread and sustained the Ebola epidemic

Frequent dispersal and short-lived local transmission clusters fuelled the 2013–2016 Ebola virus epidemic in Guinea, Liberia and Sierra Leone.

Gytis Dudas
Luiz Max Carvalho
Andrew Rambaut
Research12 Apr 2017
Nature

Volume: 544, P: 309-315
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Genome-wide association and fine-mapping analyses in ancestrally diverse populations implicate candidate causal genes and mechanisms underlying type 2 diabetes. Trans-ancestry genetic risk scores enhance transferability across populations.

Anubha Mahajan
Cassandra N. Spracklen
Andrew P. Morris
Research12 May 2022
Nature Genetics

Volume: 54, P: 560-572
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
A mind for investigation

Donald Broadbent
Books & Arts13 Feb 1986
Nature

Volume: 319, P: 545-546
Building Bacon's new engine

Donald Michie
Comments & Opinion29 Sept 1988
Nature

Volume: 335, P: 461-462
The genius phenomenon

Donald Michie
Books & Arts02 Jul 1981
Nature

Volume: 292, P: 91-92
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Multidecadal drought impacts on the Lower Colorado Basin with implications for future management

Intense droughts and irrigation over the past century in the lower Colorado Basin have driven groundwater depletion and subsidence that has been partially alleviated by transfers from the Colorado River, according to analysis of satellite, groundwater modelling, and monitoring data.

Bridget R. Scanlon
Donald R. Pool
Robert C. Reedy
ResearchOpen Access18 Mar 2025
Communications Earth & Environment

Volume: 6, P: 1-13
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

A meta-analysis of genome-wide association studies of type 2 diabetes (T2D) identifies more than 600 T2D-associated loci; integrating physiological trait and single-cell chromatin accessibility data at these loci sheds light on heterogeneity within the T2D phenotype.

Ken Suzuki
Konstantinos Hatzikotoulas
Eleftheria Zeggini
ResearchOpen Access19 Feb 2024
Nature

Volume: 627, P: 347-357
Bradykinin receptor-mediated chloride secretion in intestinal function

Donald C. Manning
Solomon H. Snyder
Michael Field
Research16 Sept 1982
Nature

Volume: 299, P: 256-259
Induction of immediate spatiotemporal changes in thalamic networks by peripheral block of ascending cutaneous information

Miguel A. L. Nicolelis
Rick C. S. Lin
John K. Chapin
Research11 Feb 1993
Nature

Volume: 361, P: 533-536
Neutrophil rolling altered by inhibition of L-selectin shedding in vitro

Bruce Walcheck
Julius Kahn
Takashi Kei Kishimoto
Research25 Apr 1996
Nature

Volume: 380, P: 720-723

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