Nature Search

Adaptive-learning physics-assisted light-field microscopy enables day-long and millisecond-scale super-resolution imaging of 3D subcellular dynamics

This paper presents an Adaptive Learning PHysics-Assisted Light-Field Microscopy (Alpha-LFM) approach, which relies on a physics-assisted deep-learning framework and adaptive-tuning strategy capable of light-field reconstruction at sub-diffraction-limit resolution. This approach enables rapid and gentle 3D imaging of subcellular dynamics.

Lanxin Zhu
Jiahao Sun
Peng Fei
ResearchOpen Access04 Aug 2025
Nature Communications

Volume: 16, P: 1-17
HDL cholesterol as a mediator of the relationship between breastfeeding and coronary atherosclerosis from a two-step Mendelian randomization analysis

Baoquan Zhang
Bin Yang
Yue Dai
ResearchOpen Access06 Aug 2025
Scientific Reports

Volume: 15, P: 1-9
Ammonia-oxidizing bacteria and archaea exhibit differential nitrogen source preferences

Isotope tracing, kinetics and transcriptomics show how members of the four AOM lineages employ different nitrogen use strategies that minimize competition for nitrogen substrates.

Wei Qin
Stephany P. Wei
Mari-Karoliina H. Winkler
Research31 Jan 2024
Nature Microbiology

Volume: 9, P: 524-536
A dedicated hypothalamic oxytocin circuit controls aversive social learning

In mice, the neural mechanisms underlying aversive social learning, specifically avoidance and fear after defeat, involve oxytocin signalling in the anterior subdivision of the ventromedial hypothalamus, ventrolateral part.

Takuya Osakada
Rongzhen Yan
Dayu Lin
Research24 Jan 2024
Nature

Volume: 626, P: 347-356
BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

The polycomb group protein BMI1 is highly expressed in prostate cancer. Here, the authors demonstrate that BMI1 directly interacts with AR leading to increased AR signaling independently of PRC1 complex and that targeting BMI1 inhibits tumor growth of castration-resistant prostate cancer tumors.

Sen Zhu
Dongyu Zhao
Qi Cao
ResearchOpen Access05 Feb 2018
Nature Communications

Volume: 9, P: 1-13
A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation

Yi et al. report that EZH2 exerts a PRC2-independent function in nucleoli, where it bridges FBL and NOP56 to facilitate rRNA methylation and subsequent IRES-dependent translation.

Yang Yi
Yanqiang Li
Qi Cao
Research01 Apr 2021
Nature Cell Biology

Volume: 23, P: 341-354
A hypothalamic pathway that suppresses aggression toward superior opponents

To fight or not to fight? Wei et al. show that Esr1 cells in the mouse cMPOA encode the fighting capability of male opponents and use this information to suppress aggression toward superior opponents by inhibiting attack-mediating ventromedial hypothalamus cells.

Dongyu Wei
Takuya Osakada
Dayu Lin
Research10 Apr 2023
Nature Neuroscience

Volume: 26, P: 774-787
A bony-crested Jurassic dinosaur with evidence of iridescent plumage highlights complexity in early paravian evolution

A number of paravian dinosaurs have been described from the Jurassic Yanliao biota, but these have tended to be morphologically similar to Archaeopteryx. Here, Hu. describe the new paravian dinosaur, Caihong juji gen. et sp. nov., which possesses a suite of unusual skeletal and feather characteristics.

Dongyu Hu
Julia A. Clarke
Xing Xu
ResearchOpen Access15 Jan 2018
Nature Communications

Volume: 9, P: 1-12
The gut microbiota metabolite trimethylamine N-oxide promotes cardiac hypertrophy by activating the autophagic degradation of SERCA2a

TMAO promotes cardiac hypertrophy via elevated intracellular Ca²⁺ levels and enhanced autophagy-mediated degradation of SERCA2a.

Dongyu Lei
Yi Liu
Ying Li
ResearchOpen Access10 Apr 2025
Communications Biology

Volume: 8, P: 1-14
Genome sequence and analysis of the tuber crop potato

Xun Xu
Shengkai Pan
Richard G. F. Visser
ResearchOpen Access10 Jul 2011
Nature

Volume: 475, P: 189-195
Video-rate 3D imaging of living cells using Fourier view-channel-depth light field microscopy

A super-resolution light-field imaging method enables video-rate 3D imaging of intracellular dynamics beyond diffraction limit and with strong noise-resistant capability.

Chengqiang Yi
Lanxin Zhu
Peng Fei
ResearchOpen Access12 Dec 2023
Communications Biology

Volume: 6, P: 1-8
MiR-204-5p may regulate oxidative stress in myopia

Bo Jiang
Nan Hong
Feng Dong
ResearchOpen Access29 Apr 2024
Scientific Reports

Volume: 14, P: 1-11
BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer

Sen Zhu
Dongyu Zhao
Qi Cao
Research28 Aug 2019
Oncogene

Volume: 39, P: 17-29
Digital twin data-driven proactive job-shop scheduling strategy towards asymmetric manufacturing execution decision

Fuqiang Zhang
Junyan Bai
Qiang Wang
ResearchOpen Access28 Jan 2022
Scientific Reports

Volume: 12, P: 1-19
Development and identification of four new synthetic hexaploid wheat lines with solid stems

Dongyu Liang
Minghu Zhang
Lianquan Zhang
ResearchOpen Access22 Mar 2022
Scientific Reports

Volume: 12, P: 1-13
A new confuciusornithid bird with a secondary epiphyseal ossification reveals phylogenetic changes in confuciusornithid flight mode

A new species of Confuciusornis, a genus of basal birds from the Early Cretaceous, reveals that these early birds had stronger flight capability and more diverse flight modes than previously expected.

Renfei Wang
Dongyu Hu
Xing Xu
ResearchOpen Access21 Dec 2022
Communications Biology

Volume: 5, P: 1-13
Three-dimensional mapping reveals heterochronic development of the neuromuscular system in postnatal mouse skeletal muscles

A comprehensive assessment of motor function and skeletal muscle development in neonatal mice provides insight into the structural status of the neuromuscular system during motor development.

Jianyi Xu
Jingtan Zhu
Dan Zhu
ResearchOpen Access08 Nov 2022
Communications Biology

Volume: 5, P: 1-14
Evaluation and practical application of prompt-driven ChatGPTs for EMR generation

Hanlin Ding
Wenjie Xia
Feng Jiang
ReviewsOpen Access02 Feb 2025
npj Digital Medicine

Volume: 8, P: 1-9

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