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Advanced filters: Author: Doreen Stimpel Clear advanced filters

  • Hereditary hypertrophic cardiomyopathy (HCM) is caused by mutations in cardiomyocyte genes, such as MYBPC3. Here, the authors use virus-mediated gene therapy to correct Mycbpc3mutations in 1-day-old mice and, by administering just a single dose, prevent development of HCM over a period of 34 weeks.

    • Giulia Mearini
    • Doreen Stimpel
    • Lucie Carrier
    Research
    Nature Communications
    Volume: 5, P: 1-10