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Showing 1–2 of 2 results
Advanced filters: Author: Doris Mia Taylor Clear advanced filters

  • Biocatalytic strategies typically transform only one alkene isomer into products, limiting the yield. Now a biocatalyst is reported to convert both isomeric silyl enol ethers into chiral α-branched ketones with high efficiency and excellent selectivity.

    • Runze Mao
    • Doris Mia Taylor
    • Frances H. Arnold
    Research
    Nature Synthesis
    Volume: 3, P: 256-264

  • Over 170 susceptibility loci have been identified by genome-wide association studies in breast cancer. Here, the authors interrogated the role of risk-associated variants from non-breast tissue, and using expression quantitative trait loci, identify potential target genes of known breast cancer susceptibility variants, as well as 11 regions not previously known to be associated with breast cancer risk.

    • Manuel A. Ferreira
    • Eric R. Gamazon
    • Georgia Chenevix-Trench
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-18