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Showing 1–3 of 3 results
Advanced filters: Author: Dorith Wunnicke Clear advanced filters
  • GltPh is a homotrimeric Na+-coupled aspartate transporter that belongs to the glutamate transporter family. The conformational changes that occur during GltPh transport are now directly observed using EPR spectroscopy, revealing that the transporting domains sample multiple states, regardless of the presence of substrate or ions.

    • Inga Hänelt
    • Dorith Wunnicke
    • Dirk Jan Slotboom
    Research
    Nature Structural & Molecular Biology
    Volume: 20, P: 210-214
  • Cells maintain membrane fluidity by regulating lipid saturation, but the molecular mechanisms of this homeoviscous adaptation remain poorly understood. Here authors reconstituted the core machinery for regulating lipid saturation in baker’s yeast to directly characterize its response to defined membrane environments and uncover its mode-of-action.

    • Stephanie Ballweg
    • Erdinc Sezgin
    • Robert Ernst
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13