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Showing 1–2 of 2 results
Advanced filters: Author: Dorothee Winterberg Clear advanced filters

  • Lassa virus is a key pathogen that can cause haemorrhagic fever and further understanding of successful therapeutic strategies are needed. Here the authors explore the use of a Lassa virus glycoprotein-based vaccine and show B cell immunity as a correlate of protection in a mouse model of vaccination and subsequent viral challenge

    • Tiago Abreu-Mota
    • Anna-Friederike Marx
    • Daniel D. Pinschewer
    ResearchOpen Access
    Nature Communications
    P: 1-20

  • Lenk et al find that the preB cell receptor (preBCR) is associated with infiltration and relapse of acute lymphoblastic leukemia in the central nervous system (CNS). They also show that downregulation of preBCR component CD79a reduces the engraftment of leukemia cells in different murine xenograft models, particularly in the CNS.

    • Lennart Lenk
    • Michela Carlet
    • Denis M. Schewe
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-6