Mucosa-associated invariant T (MAIT) cells are a recently described subset of unconventional, innate-like T cells and their development is not well understood. Here, the authors analyse MAIT cells in fetal human tissues and show that, unlike in mice, the commensal microflora is not necessary for their maturation in humans.
- Edwin Leeansyah
- Liyen Loh
- Johan K. Sandberg