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Showing 1–4 of 4 results
Advanced filters: Author: Dulguun Amgalan Clear advanced filters

  • A mouse model that replicates the clinical features of the most common form of heart failure opens a window on the mechanisms underlying this disease, and could help scientists to explore future therapies.

    • Dulguun Amgalan
    • Richard N. Kitsis
    News & Views
    Nature
    Volume: 568, P: 324-325

  • Using biochemical and NMR studies, a class of small-molecule inhibitors termed BAX activation inhibitors were found to bind directly to a previously unrecognized pocket of inactive BAX and allosterically inhibit conformational changes in BAX.

    • Thomas P. Garner
    • Dulguun Amgalan
    • Evripidis Gavathiotis
    Research
    Nature Chemical Biology
    Volume: 15, P: 322-330

  • The Impact of Genomic Variation on Function Consortium is combining single-cell mapping, genomic perturbations and predictive modelling to investigate relationships between human genomic variation, genome function and phenotypes and will provide an open resource to the community.

    • Jesse M. Engreitz
    • Heather A. Lawson
    • Ella K. Samer
    Reviews
    Nature
    Volume: 633, P: 47-57