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Showing 1–12 of 12 results
Advanced filters: Author: Dun Mao Clear advanced filters
  • Digital medicine needs intuitive readouts to translate multidimensional biomarkers into reliable cancer tests. Here, authors present EnCODE, an enzyme-driven colorimetric platform that encodes multi-miRNA profiles into decodable colours, detecting pancreatic cancer with 90% accuracy in 163 patient samples.

    • Dongsheng Mao
    • Chenbin Liu
    • Xiaoli Zhu
    ResearchOpen Access
    Nature Communications
    P: 1-16
  • Metasurfaces can be programmed for a spatial transformation of the wavefront, allowing on-chip optical signal processing. Here, the authors demonstrate a one-dimensional high-contrast transmitarray metasurface-based lens on SOI substrate and demonstrate functionalities of Fourier transformation and differentiation.

    • Zi Wang
    • Tiantian Li
    • Tingyi Gu
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-7
  • It is uncertain how much life expectancy of the Chinese population would improve under current and greater policy targets on lifestyle-based risk factors for chronic diseases and mortality behaviours. Here we report a simulation of how improvements in four risk factors, namely smoking, alcohol use, physical activity and diet, could affect mortality. We show that in the ideal scenario, that is, all people who currently smokers quit smoking, excessive alcohol userswas reduced to moderate intake, people under 65 increased moderate physical activity by one hour and those aged 65 and older increased by half an hour per day, and all participants ate 200 g more fresh fruits and 50 g more fish/seafood per day, life expectancy at age 30 would increase by 4.83 and 5.39 years for men and women, respectively. In a more moderate risk reduction scenario referred to as the practical scenario, where improvements in each lifestyle factor were approximately halved, the gains in life expectancy at age 30 could be half those of the ideal scenario. However, the validity of these estimates in practise may be influenced by population-wide adherence to lifestyle recommendations. Our findings suggest that the current policy targets set by the Healthy China Initiative could be adjusted dynamically, and a greater increase in life expectancy would be achieved.

    • Qiufen Sun
    • Liyun Zhao
    • Chan Qu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11
  • As an animal moves within its environment, self-motion signals are generated by the inner ear vestibular organs and the retina and transmitted to the CNS. In this Review, Mao and Gu describe how these multisensory signals are processed and integrated by the brain to enable self-motion perception and aid navigation.

    • Dun Mao
    • Yong Gu
    Reviews
    Nature Reviews Neuroscience
    Volume: 26, P: 715-732
  • Neurons in the retrosplenial cortex (RSC) encode spatial and navigational signals. Here the authors use calcium imaging to show that, similar to the hippocampus, RSC neurons also encode place cell-like activity in a sparse orthogonal representation, partially anchored to the allocentric cues on the linear track.

    • Dun Mao
    • Steffen Kandler
    • Vincent Bonin
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-9
  • CMOS wafer scale manufactured chiral exceptional point non-Hermitian modulators were demonstrated through AIM photonics. This enables GHz-speed asymmetric electro-optic modulation with 17 dB contrast using CMOS-compatible voltages.

    • Hwaseob Lee
    • Lorry Chang
    • Tingyi Gu
    ResearchOpen Access
    Light: Science & Applications
    Volume: 14, P: 1-10