Nature Search

Task-induced brain state manipulation improves prediction of individual traits

Decoding or predicting cognitive traits from brain activity is an exciting prospect. Here, the authors show that task-based functional connectivity better predicts intelligence-related measures than rest-based connectivity, suggesting that cognitive tasks amplify individual differences in trait-relevant circuitry.

Abigail S. Greene
Siyuan Gao
R. Todd Constable
ResearchOpen Access18 Jul 2018
Nature Communications

Volume: 9, P: 1-13
Connectome caricatures remove large-amplitude coactivation patterns in resting-state fMRI to emphasize individual differences

Dominant coactivation patterns are primarily studied in resting-state fMRI. Here, the authors study the rest of the signal, which reveals ‘caricatured’ connectomes with improved behavioral prediction.

Raimundo X. Rodriguez
Stephanie Noble
Dustin Scheinost
Research03 Nov 2025
Nature Neuroscience

Volume: 28, P: 2601-2611
Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone

Durable agonism of NPR1 achieved with a novel investigational monoclonal antibody could mirror the positive hemodynamic changes in blood pressure and heart failure identified in humans with lifelong exposure to NPR1 coding variants.

Michael E. Dunn
Aaron Kithcart
Lori Morton
ResearchOpen Access11 Sept 2024
Nature

Volume: 633, P: 654-661
A genome-first approach to aggregating rare genetic variants in LMNA for association with electronic health record phenotypes

Joseph Park
Michael G. Levin
Daniel J. Rader
Research06 Aug 2019
Genetics in Medicine

Volume: 22, P: 102-111
Data leakage inflates prediction performance in connectome-based machine learning models

The effects of data leakage on predictive models in neuroimaging studies are not well understood. Here, the authors show that data leakage via feature selection and repeated subjects drastically inflates prediction performance, whereas other forms of leakage have more minor effects.

Matthew Rosenblatt
Link Tejavibulya
Dustin Scheinost
ResearchOpen Access28 Feb 2024
Nature Communications

Volume: 15, P: 1-15
Power and reproducibility in the external validation of brain-phenotype predictions

Rosenblatt et al. run over 900 million resampling-based simulations in functional and structural connectivity data to show that low and medium effect size predictions require training and external samples in the hundreds to thousands of participants.

Matthew Rosenblatt
Link Tejavibulya
Dustin Scheinost
Research31 Jul 2024
Nature Human Behaviour

Volume: 8, P: 2018-2033
A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling

Cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) is normally induced by innate immunity sensing for protection from pathogens. Here the authors show that cGAMP is also upstream of DNA damage signaling by activating ATM-CHK2-mediated repair pathway, while simultaneously suppressing the homology-directed repair.

Daipayan Banerjee
Kurt Langberg
Nagaraj Kerur
ResearchOpen Access27 Oct 2021
Nature Communications

Volume: 12, P: 1-24
Adult stem cell activity in naked mole rats for long-term tissue maintenance

Authors report that long-term intestinal tissue maintenance in naked mole rats is achieved by having an expanded pool of slow-dividing adult stem cells while a higher proportion of differentiated cells confer enhanced function and protection to the intestinal mucosa.

Shamir Montazid
Sheila Bandyopadhyay
Shazia Irshad
ResearchOpen Access20 Dec 2023
Nature Communications

Volume: 14, P: 1-20
A hitchhiker’s guide to working with large, open-source neuroimaging datasets

Horien and colleagues provide a roadmap to working with large, publically available imaging datasets.

Corey Horien
Stephanie Noble
Dustin Scheinost
Reviews07 Dec 2020
Nature Human Behaviour

Volume: 5, P: 185-193
Early limited formula for breastfeeding infants: too much or just enough?

Miren B. Dhudasia
Dustin D. Flannery
Sagori Mukhopadhyay
Research Highlights20 Jun 2019
Journal of Perinatology

Volume: 39, P: 1149-1152
Pheromones that correlate with reproductive success in competitive conditions

Kenneth C. Luzynski
Doris Nicolakis
Dustin J. Penn
ResearchOpen Access09 Nov 2021
Scientific Reports

Volume: 11, P: 1-16
Diversity of major urinary proteins (MUPs) in wild house mice

Michaela Thoß
Viktoria Enk
Dustin J. Penn
ResearchOpen Access06 Dec 2016
Scientific Reports

Volume: 6, P: 1-9
Weak functional connectivity in the human fetal brain prior to preterm birth

Moriah E. Thomason
Dustin Scheinost
Roberto Romero
ResearchOpen Access09 Jan 2017
Scientific Reports

Volume: 7, P: 1-10
Female scent accelerates growth of juvenile male mice

Sarah M. Zala
Brian Church
Dustin J. Penn
ResearchOpen Access05 May 2023
Scientific Reports

Volume: 13, P: 1-7
Disparities in SARS-CoV-2 positivity among pregnant patients with limited English proficiency

Diana Montoya-Williams
Anne M. Mullin
Heather H. Burris
Correspondence08 Sept 2021
Journal of Perinatology

Volume: 41, P: 2564-2565
Sexual experience has no effect on male mating or reproductive success in house mice

Kerstin E. Thonhauser
Alexandra Raffetzeder
Dustin J. Penn
ResearchOpen Access21 Aug 2019
Scientific Reports

Volume: 9, P: 1-11
Regulation of volatile and non-volatile pheromone attractants depends upon male social status

M. Thoß
K. C. Luzynski
D. J. Penn
ResearchOpen Access24 Jan 2019
Scientific Reports

Volume: 9, P: 1-14
Author Correction: Regulation of volatile and non-volatile pheromone attractants depends upon male social status

M. Thoß
K. C. Luzynski
D. J. Penn
Amendments and CorrectionsOpen Access11 Apr 2019
Scientific Reports

Volume: 9, P: 1
An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

Sacha Ferdinandusse
Kirsty McWalter
Frédéric M. Vaz
ResearchOpen Access26 Nov 2020
Genetics in Medicine

Volume: 23, P: 740-750
Electronic health record phenotype in subjects with genetic variants associated with arrhythmogenic right ventricular cardiomyopathy: a study of 30,716 subjects with exome sequencing

Christopher M Haggerty
Cynthia A James
Brandon K Fornwalt
Research04 May 2017
Genetics in Medicine

Volume: 19, P: 1245-1252
Correction to: An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

Sacha Ferdinandusse
Kirsty McWalter
Frédéric M. Vaz
Amendments and CorrectionsOpen Access19 Oct 2021
Genetics in Medicine

Volume: 23, P: 2467

Search

Task-induced brain state manipulation improves prediction of individual traits

Connectome caricatures remove large-amplitude coactivation patterns in resting-state fMRI to emphasize individual differences

Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone

A genome-first approach to aggregating rare genetic variants in LMNA for association with electronic health record phenotypes

Data leakage inflates prediction performance in connectome-based machine learning models

Power and reproducibility in the external validation of brain-phenotype predictions

A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling

Adult stem cell activity in naked mole rats for long-term tissue maintenance

A hitchhiker’s guide to working with large, open-source neuroimaging datasets

Early limited formula for breastfeeding infants: too much or just enough?

Pheromones that correlate with reproductive success in competitive conditions

Diversity of major urinary proteins (MUPs) in wild house mice

Weak functional connectivity in the human fetal brain prior to preterm birth

Female scent accelerates growth of juvenile male mice

Disparities in SARS-CoV-2 positivity among pregnant patients with limited English proficiency

Sexual experience has no effect on male mating or reproductive success in house mice

Regulation of volatile and non-volatile pheromone attractants depends upon male social status

Author Correction: Regulation of volatile and non-volatile pheromone attractants depends upon male social status

An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

Electronic health record phenotype in subjects with genetic variants associated with arrhythmogenic right ventricular cardiomyopathy: a study of 30,716 subjects with exome sequencing

Correction to: An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

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