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Nature Biomedical Engineering (1)

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Leucine zipper-based immunomagnetic purification of CAR T cells displaying multiple receptors

A cell-sorting method leveraging leucine zippers allows for the generation of T cells displaying multiple chimaeric antigen receptors as well as receptors converting inhibitory signals into stimulatory signals.

Scott E. James
Sophia Chen
Marcel R. M. van den Brink
Research23 Dec 2024
Nature Biomedical Engineering

Volume: 8, P: 1592-1614

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Leucine zipper-based immunomagnetic purification of CAR T cells displaying multiple receptors

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