Nature Search

Retraction Note: Antibodies against endogenous retroviruses promote lung cancer immunotherapy

Kevin W. Ng
Jesse Boumelha
George Kassiotis
Amendments and CorrectionsOpen Access14 Jan 2026
Nature

Volume: 649, P: 1330
Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction

Studying patients with long-term diabetes who lack diabetic nephropathy reveals that targeting pyruvate kinase M2 protects against renal disease.

Weier Qi
Hillary A Keenan
George L King
Research24 Apr 2017
Nature Medicine

Volume: 23, P: 753-762
Volcanic crisis reveals coupled magma system at Santorini and Kolumbo

Seismological and geodetic data are used together with a machine learning earthquake catalogue to reconstruct magma migration before and during the 2025 volcano–tectonic crisis at Santorini volcano, indicating a coupling between Santorini and Kolumbo.

Marius P. Isken
Jens Karstens
Christian Berndt
ResearchOpen Access24 Sept 2025
Nature

Volume: 645, P: 939-945
PKM2 as a biomarker for chemosensitivity to front-line platinum-based chemotherapy in patients with metastatic non-small-cell lung cancer

C Papadaki
M Sfakianaki
J Souglakos
ResearchOpen Access18 Sept 2014
British Journal of Cancer

Volume: 111, P: 1757-1764
Dietary fructose improves intestinal cell survival and nutrient absorption

A high-fructose diet in mice improves the survival of intestinal epithelial cells, which leads to an increase in gut surface area, enhanced absorption of lipids and the promotion of tumour growth and obesity.

Samuel R. Taylor
Shakti Ramsamooj
Marcus D. Goncalves
Research18 Aug 2021
Nature

Volume: 597, P: 263-267
Demonstration of Super-X divertor exhaust control for transient heat load management in compact fusion reactors

Managing power exhaust in fusion reactors is a key challenge, especially in compact designs for cost-effective commercial energy. This study shows how alternative divertor configurations improve exhaust control, enhance stability, absorb transients and enable independent plasma regulation.

B. Kool
K. Verhaegh
V. Zamkovska
ResearchOpen Access05 Sept 2025
Nature Energy

Volume: 10, P: 1116-1131
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Machine learning methods on BioVid heat pain database for pain intensity estimation

Melpo Pittara
Andreas Anastasiou
Constantinos S. Pattichis
ResearchOpen Access31 Oct 2025
Scientific Reports

Volume: 15, P: 1-17
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Known genetic loci account for only a fraction of the genetic contribution to Alzheimer’s disease. Here, the authors have performed a large genome-wide meta-analysis comprising 409,435 individuals to discover 6 new loci and demonstrate the efficacy of an Alzheimer’s disease polygenic risk score.

Itziar de Rojas
Sonia Moreno-Grau
Agustín Ruiz
ResearchOpen Access07 Jun 2021
Nature Communications

Volume: 12, P: 1-16
Combining RAS(ON) G12C-selective inhibitor with SHP2 inhibition sensitises lung tumours to immune checkpoint blockade

GDP-bound form of KRASG12C inhibitors have been approved for the treatment of patients with advanced KRASG12C mutant non-small cell lung cancer (NSCLC), however resistance to these drugs is often observed. Here the authors report that combining a GTP-bound RAS G12C-selective inhibitor with SHP2 inhibition can sensitize lung tumours to immune checkpoint blockade.

Panayiotis Anastasiou
Christopher Moore
Julian Downward
ResearchOpen Access25 Sept 2024
Nature Communications

Volume: 15, P: 1-17
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

A small-molecule activator specific for PKM2 binds to a site distinct from the endogenous activator fructose-1,6-bisphosphate, promoting tetramerization and constitutive activation of PKM2, to inhibit xenograft tumor growth in mice.

Dimitrios Anastasiou
Yimin Yu
Matthew G Vander Heiden
Research26 Aug 2012
Nature Chemical Biology

Volume: 8, P: 839-847
RETRACTED ARTICLE: Antibodies against endogenous retroviruses promote lung cancer immunotherapy

In lung adenocarcinoma, antibodies against endogenous retroviruses promote anti-tumour activity, and expression of endogenous retroviruses can predict outcomes of immunotherapy.

Kevin W. Ng
Jesse Boumelha
George Kassiotis
ResearchOpen Access12 Apr 2023
Nature

Volume: 616, P: 563-573
Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Dimitrios Anastasiou
Yimin Yu
Matthew G Vander Heiden
Amendments and Corrections26 Nov 2012
Nature Chemical Biology

Volume: 8, P: 1008
IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

Kofuji et al. demonstrate that upregulation of IMPDH2 promotes nucleostemin stabilization and nucleoli malformation, and its inactivation induces growth arrest in glioblastoma.

Satoshi Kofuji
Akiyoshi Hirayama
Atsuo T. Sasaki
Research01 Aug 2019
Nature Cell Biology

Volume: 21, P: 1003-1014
Mixtures of genotypes increase disease resistance in a coral nursery

Anya L. Brown
Dagny-Elise Anastasiou
Thomas K. Frazer
ResearchOpen Access11 Nov 2022
Scientific Reports

Volume: 12, P: 1-6
Associations of dietary patterns with brain health from behavioral, neuroimaging, biochemical and genetic analyses

Using a large sample from the UK Biobank, the authors investigate the effects of dietary patterns on multiple aspects of brain health and mental health.

Ruohan Zhang
Bei Zhang
Wei Cheng
ResearchOpen Access01 Apr 2024
Nature Mental Health

Volume: 2, P: 535-552
Reducing the resources required by ADAPT-VQE using coupled exchange operators and improved subroutines

Mafalda Ramôa
Panagiotis G. Anastasiou
Sophia E. Economou
ResearchOpen Access26 May 2025
npj Quantum Information

Volume: 11, P: 1-19
Key informants’ perspectives about sexual victimisation of learners with intellectual disability in South Africa

Tlakale Nareadi Phasha
ResearchOpen Access01 Apr 2022
Humanities and Social Sciences Communications

Volume: 9, P: 1-8
Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Itziar de Rojas
Sonia Moreno-Grau
Agustín Ruiz
Amendments and CorrectionsOpen Access09 Feb 2023
Nature Communications

Volume: 14, P: 1-2
Relation of the Mediterranean diet with the incidence of gestational diabetes

B Karamanos
A Thanopoulou
C Savona-Ventura
Research02 Oct 2013
European Journal of Clinical Nutrition

Volume: 68, P: 8-13
Antibacterial properties and regenerative potential of Sr²⁺ and Ce³⁺ doped fluorapatites; a potential solution for peri-implantitis

A. D. Anastasiou
M. Nerantzaki
D. Bikiaris
ResearchOpen Access09 Oct 2019
Scientific Reports

Volume: 9, P: 1-11
Divertor shaping with neutral baffling as a solution to the tokamak power exhaust challenge

Power exhaust is one of the biggest challenges stopping fusion energy. This article shows experimental evidence for strategically shaping the power exhaust region as a solution to this challenge, utilising physics understanding to strike a balance between engineering complexity and power exhaust benefits, consistent with reduced models and simulations.

Kevin Verhaegh
James Harrison
V. Zamkovska
ResearchOpen Access23 May 2025
Communications Physics

Volume: 8, P: 1-15
Feasibility of low-cost particle sensor types in long-term indoor air pollution health studies after repeated calibration, 2019–2021

Elle Anastasiou
M. J. Ruzmyn Vilcassim
Terry Gordon
ResearchOpen Access26 Aug 2022
Scientific Reports

Volume: 12, P: 1-8
Targeting allosteric regulation of cancer metabolism

New research has revealed a wealth of small molecules that target cancer-specific metabolic vulnerabilities by targeting allosteric sites. Here, a Perspective discusses how their application has provided insights into cancer metabolism and therapy.

Daniel M. Kremer
Costas A. Lyssiotis
Reviews28 Apr 2022
Nature Chemical Biology

Volume: 18, P: 441-450

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