Nature Search

Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F

Liang Cao
Barbara Faha
Nicholas Dyson
Research09 Jan 1992
Nature

Volume: 355, P: 176-179
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

Peter Whyte
Karen J. Buchkovich
Ed Harlow
Research14 Jul 1988
Nature

Volume: 334, P: 124-129
Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

Li-Huei Tsai
Ed Harlow
Matthew Meyerson
Research12 Sept 1991
Nature

Volume: 353, P: 174-177
SV40 T antigen binds specifically to a cellular 53 K protein in vitro

Frank McCormick
Robin Clark
Robert Tjian
Research02 Jul 1981
Nature

Volume: 292, P: 63-65
p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

Li-Huei Tsai
Ivana Delalle
Ed Harlow
Research29 Sept 1994
Nature

Volume: 371, P: 419-423
Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

James Koh
Greg H. Enders
Ed Harlow
Research08 Jun 1995
Nature

Volume: 375, P: 506-510
For our eyes only

Ed Harlow
News & Views24 Sept 1992
Nature

Volume: 359, P: 270-271
Two different viral transforming proteins bind the same host tumour antigen

David Lane
Ed Harlow
News & Views05 Aug 1982
Nature

Volume: 298, P: 517
Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs

Tamara Zarkowska
Sally U
Sibylle Mittnacht
Research16 Jan 1997
Oncogene

Volume: 14, P: 249-254
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
A component of the transcriptional represser MeCP1 shares a motif with DNA methyltransferase and HRX proteins

Sally H. Cross
Richard R. Meehan
Adrian Bird
Research01 Jul 1997
Nature Genetics

Volume: 16, P: 256-259
Absence of TSG101 transcript abnormalities in human cancers

Barry Trink
Sara I Pai
David Sidransky
Research04 Jun 1998
Oncogene

Volume: 16, P: 2815-2818
Provocative questions in cancer research

Harold Varmus and Ed Harlow explain how an innovative initiative is opening up neglected areas of oncology.

Harold Varmus
Ed Harlow
Comments & Opinion25 Jan 2012
Nature

Volume: 481, P: 436-437
Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/−) mice

Lili Yamasaki
Roderick Bronson
Tyler Jacks
Research01 Apr 1998
Nature Genetics

Volume: 18, P: 360-364
Tumour-suppressor genes: evolving definitions in the genomic age

Daniel Haber
Ed Harlow
News & Views01 Aug 1997
Nature Genetics

Volume: 16, P: 320-322
SARS-CoV-2 evolution during treatment of chronic infection

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Research05 Feb 2021
Nature

Volume: 592, P: 277-282
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Research11 Mar 2021
Nature

Volume: 593, P: 136-141
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFκB p65 protein expression

Roberta Visconti
Janete Cerutti
Alfredo Fusco
Research16 Oct 1997
Oncogene

Volume: 15, P: 1987-1994
Glutamate-receptor-mediated encoding and retrieval of paired-associate learning

M. Day
R. Langston
R. G. M. Morris
Research10 Jul 2003
Nature

Volume: 424, P: 205-209
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
The retinoblastoma tumour suppressor in development and cancer

Marie Classon
Ed Harlow
Reviews01 Dec 2002
Nature Reviews Cancer

Volume: 2, P: 910-917
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by ¹⁹F-Magnetic Resonance Spectroscopy

Gregorio Naredo-Gonzalez
Rita Upreti
Ruth Andrew
ResearchOpen Access29 Sept 2022
Scientific Reports

Volume: 12, P: 1-13
Dermal bacterial LPS-stimulation reduces susceptibility to intradermal Trypanosoma brucei infection

Omar A. Alfituri
Enock M. Mararo
Neil A. Mabbott
ResearchOpen Access10 May 2021
Scientific Reports

Volume: 11, P: 1-10
Ablation of the androgen receptor from vascular smooth muscle cells demonstrates a role for testosterone in vascular calcification

Dongxing Zhu
Patrick W. F. Hadoke
Vicky E. MacRae
ResearchOpen Access20 Apr 2016
Scientific Reports

Volume: 6, P: 1-9
Interferon-α induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway that is antagonized by epidermal growth factor

M Caraglia
A Abbruzzese
P Tagliaferri
Research27 Aug 1999
Cell Death & Differentiation

Volume: 6, P: 773-780
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Protein neddylation: beyond cullin–RING ligases

Post-translational modification of proteins by NEDD8 has been mainly characterized in terms of the cullin–RING E3 ligase family. However, recent studies have indicated that there might be non-cullin neddylation targets that require further verification.

Radoslav I. Enchev
Brenda A. Schulman
Matthias Peter
Reviews22 Dec 2014
Nature Reviews Molecular Cell Biology

Volume: 16, P: 30-44
Key role of the cyclin-dependent kinase inhibitor p27^kip1 for embryonal carcinoma cell survival and differentiation

Gustavo Baldassarre
Maria Vittoria Barone
Giuseppe Viglietto
Research18 Nov 1999
Oncogene

Volume: 18, P: 6241-6251
Sibling rivalry in the E2F family

Jeffrey M. Trimarchi
Jacqueline A. Lees
Reviews01 Jan 2002
Nature Reviews Molecular Cell Biology

Volume: 3, P: 11-20
Spindle regulation in neural precursors of flies and mammals

The mitotic spindle is crucial for cell division and might have an important role in segregating cell fate determining factors. Buchman and Tsai review studies investigating spindle regulation duringDrosophila melanogasterneuroblast mitosis and relate this to our understanding of mammalian neurogenesis.

Joshua J. Buchman
Li-Huei Tsai
Reviews17 Jan 2007
Nature Reviews Neuroscience

Volume: 8, P: 89-100

Search

Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

SV40 T antigen binds specifically to a cellular 53 K protein in vitro

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

For our eyes only

Two different viral transforming proteins bind the same host tumour antigen

Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

A component of the transcriptional represser MeCP1 shares a motif with DNA methyltransferase and HRX proteins

Absence of TSG101 transcript abnormalities in human cancers

Provocative questions in cancer research

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/−) mice

Tumour-suppressor genes: evolving definitions in the genomic age

SARS-CoV-2 evolution during treatment of chronic infection

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Genetic mechanisms of critical illness in COVID-19

Whole-genome sequencing reveals host factors underlying critical COVID-19

Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFκB p65 protein expression

Glutamate-receptor-mediated encoding and retrieval of paired-associate learning

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

The retinoblastoma tumour suppressor in development and cancer

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by ¹⁹F-Magnetic Resonance Spectroscopy

Dermal bacterial LPS-stimulation reduces susceptibility to intradermal Trypanosoma brucei infection

Ablation of the androgen receptor from vascular smooth muscle cells demonstrates a role for testosterone in vascular calcification

Interferon-α induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway that is antagonized by epidermal growth factor

Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Protein neddylation: beyond cullin–RING ligases

Key role of the cyclin-dependent kinase inhibitor p27^kip1 for embryonal carcinoma cell survival and differentiation

Sibling rivalry in the E2F family

Spindle regulation in neural precursors of flies and mammals

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