Nature Search

Molecular characterisation of 10 Dutch properdin type I deficient families: mutation analysis and X-inactivation studies

Ruud van den Bogaard
Cees AP Fijen
Marcel MAM Mannens
Research24 Jul 2000
European Journal of Human Genetics

Volume: 8, P: 513-518
Plasmid-mediated metronidazole resistance in Clostridioides difficile

Cases of C. difficile (CD) resistant to metronidazole have been reported but the mechanism remains enigmatic. Here the authors identify a plasmid, which correlates with metronidazole resistance status in a large international collection of CD isolates, and demonstrate that the plasmid can confer metronidazole resistance.

Ilse M. Boekhoud
Bastian V. H. Hornung
Wiep Klaas Smits
ResearchOpen Access30 Jan 2020
Nature Communications

Volume: 11, P: 1-12
Emergence and global spread of epidemic healthcare-associated Clostridium difficile

Trevor Lawley and colleagues report whole-genome sequencing of a large global collection of Clostridium difficile, the most common cause of healthcare-associated infection in the developed world. Their phylogenetic analysis traces the spread of this pathogen through healthcare-associated epidemics worldwide.

Miao He
Fabio Miyajima
Trevor D Lawley
Research09 Dec 2012
Nature Genetics

Volume: 45, P: 109-113
High prevalence of Clostridiodes diffiicle PCR ribotypes 001 and 126 in Iran

Akram Baghani
Alireza Mesdaghinia
Masoumeh Douraghi
ResearchOpen Access13 Mar 2020
Scientific Reports

Volume: 10, P: 1-9
Adaptation of host transmission cycle during Clostridium difficile speciation

Genomic analysis of 906 Clostridium difficile strains shows that this enteropathogen is undergoing speciation, which is linked to the selection of genes involved in sporulation and in the metabolism of simple dietary sugars.

Nitin Kumar
Hilary P. Browne
Trevor D. Lawley
Research12 Aug 2019
Nature Genetics

Volume: 51, P: 1315-1320
Molecular characterization of MRSA collected during national surveillance between 2008 and 2019 in the Netherlands

Schouls et al. characterize 43,321 methicillin-resistant Staphylococcus aureus (MRSA) isolates obtained between 2008 and 2019 in the Netherlands. Genomic changes occur in the MRSA population, with increases in the proportion of PVL-positive MRSA.

Leo M. Schouls
Sandra Witteveen
R. Steingrover
ResearchOpen Access12 Sept 2023
Communications Medicine

Volume: 3, P: 1-13
Tackling the emerging threat of antifungal resistance to human health

The impacts of fungal infections on human health are of increasing concern, and resistance of pathogenic fungi to all licensed systemic antifungals has been documented. In this Review, Fisher, Verweij and colleagues discuss the research and innovation topics that are needed to understand and minimize the occurrence and impact of antifungal resistance.

Matthew C. Fisher
Ana Alastruey-Izquierdo
Paul E. Verweij
Reviews29 Mar 2022
Nature Reviews Microbiology

Volume: 20, P: 557-571
A prospective matched case-control study on the genomic epidemiology of colistin-resistant Enterobacterales from Dutch patients

Vendrik et al performed a prospective matched case-control study on the genomic epidemiology of colistin-resistant Escherichia coli and Klebsiella pneumoniae from Dutch patients. Colistin resistance is present, but uncommon in the Netherlands and caused by the mcr gene in a minority of colistin-resistant isolates.

Karuna E. W. Vendrik
Angela de Haan
Karin van Dijk
ResearchOpen Access20 May 2022
Communications Medicine

Volume: 2, P: 1-12
Clostridium difficile infection

This Primer describes the mechanisms underlying the serious effects of Clostridium difficile infection, which is the leading cause of health-care-associated infective diarrhoea. Strategies for diagnosis, prevention and management are also described, illustrating the burden that C. difficile infection places on patients and society.

Wiep Klaas Smits
Dena Lyras
Ed J. Kuijper
Reviews07 Apr 2016
Nature Reviews Disease Primers

Volume: 2, P: 1-20
Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans

Frank Fleurbaaij
Alex A. Henneman
Paul J. Hensbergen
ResearchOpen Access25 May 2018
Scientific Reports

Volume: 8, P: 1-12
Intestinal permeability before and after albendazole treatment in low and high socioeconomic status schoolchildren in Makassar, Indonesia

Aldian I. Amaruddin
Jan Pieter R. Koopman
Maria Yazdanbakhsh
ResearchOpen Access01 Mar 2022
Scientific Reports

Volume: 12, P: 1-11

Search

Molecular characterisation of 10 Dutch properdin type I deficient families: mutation analysis and X-inactivation studies

Plasmid-mediated metronidazole resistance in Clostridioides difficile

Emergence and global spread of epidemic healthcare-associated Clostridium difficile

High prevalence of Clostridiodes diffiicle PCR ribotypes 001 and 126 in Iran

Adaptation of host transmission cycle during Clostridium difficile speciation

Molecular characterization of MRSA collected during national surveillance between 2008 and 2019 in the Netherlands

Tackling the emerging threat of antifungal resistance to human health

A prospective matched case-control study on the genomic epidemiology of colistin-resistant Enterobacterales from Dutch patients

Clostridium difficile infection

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans

Intestinal permeability before and after albendazole treatment in low and high socioeconomic status schoolchildren in Makassar, Indonesia

Search

Quick links

Search

Filter By:

Search

Quick links