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  • Tryptophan depletion in melanoma cells after prolonged treatment with interferon-γ (IFNγ) results in ribosomal frameshifting and the production of aberrant peptides that can be presented to T cells and induce an immune response.

    • Osnat Bartok
    • Abhijeet Pataskar
    • Reuven Agami
    Research
    Nature
    Volume: 590, P: 332-337