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Advanced filters: Author: Edgar Gonzalez-Rodriguez Clear advanced filters

  • The xylosyltransferase isoenzymes XT1 and XT2 catalyze the first glycosylation step in the biosynthesis of proteoglycans. Now, bump-and-hole engineering of XT1 and XT2 enables substrate profiling and modification of proteins as designer proteoglycans to modulate cellular behavior.

    • Zhen Li
    • Himanshi Chawla
    • Benjamin Schumann
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 22, P: 612-621