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Showing 1–5 of 5 results
Advanced filters: Author: Edward Emmott Clear advanced filters

  • During SARS-CoV-2 replication, viral and cellular proteases play crucial roles and have been shown to be promising anti-viral targets. Here, Meyer et al. apply mass spectrometry to characterize the proteolytic cleavage profile of viral and cellular proteins in vitro.

    • Bjoern Meyer
    • Jeanne Chiaravalli
    • Edward Emmott
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16

  • Prioritized Single-Cell ProtEomics (pSCoPE) introduces the concept of using priority levels that define the temporal order of peptide analysis for single-cell proteomic analysis. Prioritized data acquisition aims to simultaneously optimize the consistency, sensitivity, depth and accuracy of protein quantification.

    • R. Gray Huffman
    • Andrew Leduc
    • Nikolai Slavov
    ResearchOpen Access
    Nature Methods
    Volume: 20, P: 714-722

  • Biological systems can now be studied at the single-cell level using mass spectrometry. In Single Cell ProtEomics (SCoPE2), a carrier sample is used to enhance peptide sequence identification with multiplexed analysis using isobaric mass tags.

    • Aleksandra A. Petelski
    • Edward Emmott
    • Nikolai Slavov
    Protocols
    Nature Protocols
    Volume: 16, P: 5398-5425

  • Drawing from real-life scenarios and insights shared at the RAISE (Responsible AI for Social and Ethical Healthcare) conference, we highlight the critical need for AI in health care (AIH) to primarily benefit patients and address current shortcomings in health care systems such as medical errors and access disparities.

    • Carey Beth Goldberg
    • Laura Adams
    • Jianfei Zhao
    Comments & Opinion
    Nature Medicine
    Volume: 30, P: 623-627