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Mucosal Immunology (2)
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Showing 1–5 of 5 results

Advanced filters: Author: Edward N. Janoff Clear advanced filters

Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease

Pathogenic IgA1 metalloproteases block the initial host immune response by cleaving host IgA1. Using cryoEM, the authors here provide structural insights into the substrate recognition mechanism of Streptococcus pneumoniae IgA1 protease, and develop a protease-inhibiting antibody.

Zhiming Wang
Jeremy Rahkola
Elan Eisenmesser
ResearchOpen Access27 Nov 2020
Nature Communications

Volume: 11, P: 1-8
Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19

Xiyuan Bai
Ashley M. Buckle
Edward D. Chan
ResearchOpen Access25 Mar 2022
Scientific Reports

Volume: 12, P: 1-14
Limited expression of APRIL and its receptors prior to intestinal IgA plasma cell development during human infancy

C E Gustafson
D Higbee
E N Janoff
Research18 Sept 2013
Mucosal Immunology

Volume: 7, P: 467-477
Pneumococcal IgA1 protease subverts specific protection by human IgA1

E N Janoff
J B Rubins
J N Weiser
Research03 Jul 2013
Mucosal Immunology

Volume: 7, P: 249-256
Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19

Xiyuan Bai
Ashley M. Buckle
Edward D. Chan
Amendments and CorrectionsOpen Access19 Apr 2022
Scientific Reports

Volume: 12, P: 1-2