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Showing 1–3 of 3 results
Advanced filters: Author: Edward Vigmond Clear advanced filters

  • Qian et al. used cardiac magnetic resonance images and electrocardiograms from the UK Biobank and an ischemic heart disease cohort and developed more than 3,500 cardiac digital twins. They demonstrate that the myocardial anatomy causes differences in the QRS duration among sexes while age and body weight alter potassium conductance and myocardial conduction velocity.

    • Shuang Qian
    • Devran Ugurlu
    • Steven Niederer
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 4, P: 624-636

  • The Purkinje system can be a source of arrhythmias and has been shown to trigger ventricular fibrillation. The complexity of the molecular mechanisms of ventricular fibrillation, and the incomplete understanding of Purkinje arrhythmogenicity, make the identification of vulnerable individuals challenging. In this Review, Haissaguerre and colleagues discuss the current knowledge of the pathophysiological mechanisms underlying Purkinje-related arrhythmias, and highlight the current therapeutic options.

    • Michel Haissaguerre
    • Edward Vigmond
    • Olivier Bernus
    Reviews
    Nature Reviews Cardiology
    Volume: 13, P: 155-166