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Advanced filters: Author: Edwin Alfonzo Clear advanced filters

  • The design of complementary catalysts to target different C–H bonds in a specific molecule is challenging. Now, a pair of P450-based carbene transferase enzymes is engineered, which can selectively cyanomethylate either a C(sp3)–H or arene C(sp2)–H bond present in the same substrate.

    • Juner Zhang
    • Ailiena O. Maggiolo
    • Frances H. Arnold
    Research
    Nature Catalysis
    Volume: 6, P: 152-160