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Showing 1–2 of 2 results
Advanced filters: Author: Edwin Leeansyah Clear advanced filters

  • Mucosa-associated invariant T (MAIT) cells are a recently described subset of unconventional, innate-like T cells and their development is not well understood. Here, the authors analyse MAIT cells in fetal human tissues and show that, unlike in mice, the commensal microflora is not necessary for their maturation in humans.

    • Edwin Leeansyah
    • Liyen Loh
    • Johan K. Sandberg
    ResearchOpen Access
    Nature Communications
    Volume: 5, P: 1-10

  • Here, using longitudinal pre- and post-infection samples from the RV217 Early Capture HIV Cohort Study, the authors show that mucosa-associated invariant T (MAIT) cells become activated and expand during the early acute phase of HIV infection, with subsequent reprogramming towards innate-like functionality.

    • Kerri G. Lal
    • Dohoon Kim
    • Johan K. Sandberg
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13