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Advanced filters: Author: Eftychia Kyriacou Clear advanced filters

Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8

The meiotic proteins Spo11 and Rec8, which ensure meiotic recombination and reductional chromosome segregation, have additional activities that challenge centromere stability by promoting centromeric nucleosome remodelling in both fission yeast and human cells.

Haitong Hou
Eftychia Kyriacou
Julia Promisel Cooper
Research03 Mar 2021
Nature

Volume: 591, P: 671-676
Spotiflow: accurate and efficient spot detection for fluorescence microscopy with deep stereographic flow regression

Spotiflow uses deep learning for subpixel-accurate spot detection in diverse 2D and 3D images. The improved accuracy offered by Spotiflow enables improved biological insights in both iST and live imaging experiments.

Albert Dominguez Mantes
Antonio Herrera
Martin Weigert
Research06 Jun 2025
Nature Methods

Volume: 22, P: 1495-1504

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Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8

Spotiflow: accurate and efficient spot detection for fluorescence microscopy with deep stereographic flow regression

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