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Showing 1–7 of 7 results
Advanced filters: Author: Elena De Petrillo Clear advanced filters

  • Here the authors report that using an “isogenomic” reference genome (fully matched to the experimental cell line) improves the accuracy of genomic, epigenomic and transcriptomic analyses, as well as genome editing, compared to a non-matched generic reference.

    • Luca Corda
    • Emilia Volpe
    • Simona Giunta
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • The authors present a diploid reference-quality genome assembly of the widely used cell line RPE-1, revealing heightened variation between haplotypes and other human genomes at centromeres. The availability of a reference genome matching the cell line under study promises a new era of high-precision haplotype-resolved functional genomics.

    • Emilia Volpe
    • Alessio Colantoni
    • Simona Giunta
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15

  • About 45% of terrestrial precipitation originates from land evaporation, highlighting the role of land use in the global water cycle, as revealed by improved high-resolution atmospheric moisture flows reconciled with reanalysis data through the Iterative Proportional Fitting.

    • Elena De Petrillo
    • Simon Felix Fahrländer
    • Francesco Laio
    ResearchOpen Access
    Communications Earth & Environment
    Volume: 6, P: 1-13

  • Site-selective modification of symmetrical concave molecules is a highly challenging task because of the rapid increase in potential combinations as the number of sites increases. Here, the authors show routes to selectively functionalize six symmetrical positions, leading to a hexa-differentiated α-cyclodextrin.

    • Bo Wang
    • Elena Zaborova
    • Matthieu Sollogoub
    Research
    Nature Communications
    Volume: 5, P: 1-7

  • Virtual water flows embodied in the international food trade by the largest companies can exceed those of entire nations highlighting the importance of corporations for water stewardship and security, suggests an analysis of the top 9 transnational corporations exporting Brazilian soy.

    • Elena De Petrillo
    • Marta Tuninetti
    • Francesco Laio
    ResearchOpen Access
    Communications Earth & Environment
    Volume: 4, P: 1-12