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Advanced filters: Author: Elisa M. Crombie Clear advanced filters

  • The group of Shih-Yin Tsai observed age-associated neuromuscular junction structural instability in male but not female mice which is driven by dysregulation of mTOR complex 1 activity. Genetic activation of the downstream phosphorylation target 4EBP1 in the muscle remodeled the neuromuscular junction and enhanced synaptic transmission.

    • Seok-Ting J. Ang
    • Elisa M. Crombie
    • Shih-Yin Tsai
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15