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Advanced filters: Author: Elisa Sefora Pierobon Clear advanced filters

  • Cachexia is a metabolic syndrome leading to muscle and adipose tissue loss in majority of cancer patients. Here the authors show that, in a mouse model, BET inhibitor JQ1 counteracts muscle and adipose tissue wasting tempering cachexia and prolonging survival through a mechanism unrelated to tumour growth.

    • Marco Segatto
    • Raffaella Fittipaldi
    • Giuseppina Caretti
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-16