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Showing 1–4 of 4 results

Advanced filters: Author: Elisabeth Berber Clear advanced filters

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

The Sir2 family member SIRT6 is an NAD-dependent, histone H3 lysine 9 deacetylase enzyme that modulates telomeric chromatin and is required for stable association of WRN, the factor that is mutated in Werner Syndrome.

Eriko Michishita
Ronald A. McCord
Katrin F. Chua
Research12 Mar 2008
Nature

Volume: 452, P: 492-496
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1

The detrimental effects of aged blood on cognition and nervous system function in mice can be combatted by targeting brain endothelial cell dysfunction via inhibition of aberrant VCAM1 signaling at the blood–brain barrier.

Hanadie Yousef
Cathrin J. Czupalla
Tony Wyss-Coray
Research13 May 2019
Nature Medicine

Volume: 25, P: 988-1000
SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

Shivani Malik
Lidia Villanova
Katrin F. Chua
ResearchOpen Access29 Apr 2015
Scientific Reports

Volume: 5, P: 1-9
Involvement of Monocyte Subsets in the Immunopathology of Giant Cell Arteritis

Yannick van Sleen
Qi Wang
Elisabeth Brouwer
ResearchOpen Access26 Jul 2017
Scientific Reports

Volume: 7, P: 1-11